Cardiovascular diseases are the leading causes of death worldwide and represent a substantial economic burden on public health care systems. Now, a study from researchers at Uppsala University shows that … Continue Reading Large-scale study shows that memory, epigenetics of a heart attack are stored in person’s genes.
The children of traumatized people have long been known to be at increased risk for post-traumatic stress disorder (PTSD). However, there are very few opportunities to examine biologic alterations in … Continue Reading Trauma’s inherited epigenetic fingerprint observed in children of Holocaust survivors.
Epigenetics is a research field where DNA methylation or histone acetylation, as opposed to the DNA sequence, are studied as a tool for conveying traits to the next generation. Previously, … Continue Reading New type of epigenetic mark identified in the human cell nucleus.
Obesity has become a major health threat, affecting more than half a billion people worldwide in 2014. In particular, obesity increases the risk for insulin resistance, hypertension, coronary heart disease … Continue Reading Epigenetic modification which raises obesity risk and predicts fatty liver identified.
Mitochondria are the cellular powerplant and, reliant on nutrient status, it is known that Vitamin B turns mitochondria into cellular builders. Through vitamin B, mitochondria produce substances to make ingredients … Continue Reading Mitochondria dysfunction shown to cause vitamin b imbalance and genetic changes.
As the population continues to age, the need for biological measures of age and more precise screening tests for age-related diseases is becoming increasingly urgent. Epigenetics serves as an intersection … Continue Reading New epigenetic predictor of cancer validated in human study.
Type 2 diabetes is a chronic illness characterised by the presence of elevated blood glucose levels. It accounts for between 80 and 90% of diabetes cases and is one of … Continue Reading Large-scale study identifies an epigenetic marker for Type 2 diabetes.
Herpes simplex virus (HSV) is found in the brain cells of approximately 90% of the world’s population and leads to cold sores, recurrent eye infections, genital lesions, and in rare … Continue Reading Study shows how the herpes simplex virus reactivates in neurons.
Obesity is a metabolic disorder resulting from behavioral and heritable causes. Children of obese fathers are at higher risk of developing metabolic disease later in life, independent of the body … Continue Reading Study maps epigenetics of father’s weight passed on by his sperm.
DNA methylation is essential for the proper control of gene expression and cell identity, what enables cells with the same genetic material to become, for example, a nerve cell, a … Continue Reading Single-cell imaging developed which can record DNA methylation in real time.
Methylation is a process where a methyl group is added into critical points along human DNA. In cancer, many regions of the DNA are not methylated, leading to untimely gene … Continue Reading Researchers identify an epigenetic mechanism for colon cancer proliferation.
After it is transcribed from DNA, RNA can go on to many fates. While the most familiar path may lead directly to the production of protein, RNA molecules themselves can … Continue Reading Researchers unlock another piece of the RNA sequencing puzzle.
Cancer’s ability to grow unchecked is often attributed to cancer stem cells, a small fraction of cancer cells that have the capacity to grow and multiply indefinitely. How cancer stem … Continue Reading Researchers begin to map the epigenetic tags of glioblastoma.
Researchers at the University of Illinois have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells, the specialized cells that form blood vessels. Understanding the … Continue Reading Researchers begin to map the epigenetics that turn stem cells into blood vessel cells.
The results of a study presented today at the European League Against Rheumatism Annual Congress revealed that DNA methylation, a mechanism that regulates gene expression, could influence the progression of … Continue Reading First ever study maps the epigenetics of AS development caused by environmental factors.
Researchers at the University of Toronto have uncovered new insights on the genetic causes of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease. These findings could uncover a … Continue Reading Human generational study pinpoints epigenetic cause of Amyotrophic Lateral Sclerosis (ALS).