The brain is the key regulator of appetite, body weight, and metabolism, controlling the passage of every nutrient that enters and exits the body. Specifically, there is a small group … Continue Reading Study finds small colony of neurons modulate amount of insulin the pancreas produces.
Parkinson’s disease (PD) is a degenerative neurological disease characterized by tremor, slowness, and gait and balance difficulties that affects approximately 1 million people in the United States. The symptoms are … Continue Reading Study identifies key to Parkinson’s disease neurodegeneration.
Mitochondria, often called the cell’s energy powerhouse, are small organelles which reside in a cell’s cytoplasm and convert food into energy or building blocks. Mutations in mitochondrial DNA, or mtDNA, … Continue Reading Performing single-cell surgery with a laser-powered nanoblade.
It is known that cell death is a mechanism used by multicellular organisms to help them survive by removing infected, damaged or unwanted cells. Mitochondria are known as the energy-generating … Continue Reading Researchers identify previously unknown pathway for cell death.
Mitochondria are the cellular powerplant and, reliant on nutrient status, it is known that Vitamin B turns mitochondria into cellular builders. Through vitamin B, mitochondria produce substances to make ingredients … Continue Reading Mitochondria dysfunction shown to cause vitamin b imbalance and genetic changes.
A large body of data gathered over the last decades has identified the neuronal pathways which link the central nervous system with the autonomic innervation of the endocrine pancreas. These … Continue Reading Study shows brain cell mitochondria controls blood-sugar levels after a meal.
Age is the largest risk factor for numerous pathologies, ranging from neurodegeneration to cancer. These pathologies likely arise from a loss of tissue homeostasis driven by one or more basic … Continue Reading New role for mitochondria identified in cellular senescence and aging.
High blood sugar is a defining characteristic of Type 2 diabetes and the cause of many of the condition’s complications, including kidney failure, heart disease, and blindness. Most diabetes medications … Continue Reading Researchers block mitochondrial glucose production to treat type 2 diabetes in preclinical trials.
Free radicals are especially reactive atoms or groups of atoms that have one or more unpaired electrons. They are produced in the body as a by-product of normal metabolism and … Continue Reading New findings on the free radical theory of aging and mitochondrial damage.
Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been … Continue Reading New diagnostic identifies mitochondria dysfunction in Type 2 diabetes.
In a life-threatening situation, the heart beats faster and harder, invigorated by the fight-or-flight response, which instantaneously prepares a person to react or run. Now, a new study by researchers … Continue Reading Researchers map how calcium uptake in mitochondria during a heart attack causes large cell death.
Scientists from the Institut Pasteur, CNRS, Institut Gustave Roussy and CEA, have succeeded in restoring normal activity in cells isolated from patients with the premature aging disease Cockayne syndrome. They … Continue Reading Researchers identify and correct premature aging in diseased cells.
Mitochondrial diseases are maternally inherited genetic disorders that cause a wide spectrum of debilitating conditions and which currently have no cure. In a new opensource study published in the journal … Continue Reading Researchers successfully ‘edit’ mitochondrial DNA to prevent inherited disease in animal model.
An experimental drug that attacks brain tumour tissue by crippling the cells’ energy source called the mitochondria has passed early tests in animal models and human tissue cultures, state researchers … Continue Reading Selective mitochondrial chemotherapy, decimates brain tumours and headed for human trials.
Scientists at the University of California, Berkeley, have identified a new molecular pathway critical to aging, and confirmed that the process can be manipulated to help make old blood like … Continue Reading Researchers identify new mitochondrial pathway critical to aging.
Connection between mitochondria, shortened telomeres and psychiatric disorders seen at a cellular level.
Researchers from Butler Hospital have identified an association between biological changes on the cellular level and both childhood adversity and psychiatric disorders. These changes in the form of telomere shortening … Continue Reading Connection between mitochondria, shortened telomeres and psychiatric disorders seen at a cellular level.