Nanomachines made from synthetic DNA motors have the potential to mimic natural protein motors in cells, however, the operation of synthetic DNA motors in living corpuscles has not yet been … Continue Reading Autonomous nanomachines perform biologic functions in live cells.
Semen quality is a measure of the ability of semen to accomplish fertilization and a measure of fertility in a man. It is the sperm in the semen that are … Continue Reading ‘Spermbots’ successful in proof-of-concept fertility studies.
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons. This fatal disease is characterized by progressive muscular atrophy and doesn’t have an effective treatment. Patients with … Continue Reading Study provides first definitive evidence and description of protein clump toxicity in ALS.
Dopamine deficiency in the basal ganglia is known to cause severe motor dysfunctions such as slowness of movement, or bradykinesia, as seen in Parkinson’s disease. Dopamine binds D1 and D2 receptors … Continue Reading Study identifies the cause of slowness of movement in Parkinson’s disease.
When a person walks around the block, their body is mostly on autopilot; they don’t have to consciously think about alternating each step or which muscles it takes to lift … Continue Reading Researchers visualise motor neurons in real-time on a genetic sub-type level.
Autism is a lifelong neurodevelopmental disorder that affects how a person communicates with, and relates to, other people. Repetitive and restricted behaviour is perhaps the most widely recognized of the … Continue Reading Neuroimaging maps behaviour, brain structure difference in girls and boys with autism.
Parkinson’s disease (PD) belongs to a group of conditions called motor system disorders, which are the result of the loss of dopamine-producing brain cells. The four primary symptoms of PD … Continue Reading Study shows magnetic stimulation effectively treats frozen gait in Parkinson’s.
A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If not, the defective … Continue Reading Researchers identify the role mitochondria plays in familial ALS.
Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords, according to a … Continue Reading Paralyzed men move legs with new non-invasive spinal cord stimulation.
Researchers from the NYU Langone Medical Center and New York University have demonstrated that a specialized DNA-binding protein called CTCF is essential for the precise expression of genes that control … Continue Reading Researchers identify specialized protein crucial for normal neurodevelopment.
First detailed blueprint for a spinal circuit for integrating motor and sensory commands from the brain.
Walking across an icy parking lot in winter, and remaining upright, takes intense concentration. But a new discovery suggests that much of the balancing act that the human body performs … Continue Reading First detailed blueprint for a spinal circuit for integrating motor and sensory commands from the brain.
For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a … Continue Reading Researchers identify mechanism of upper motor neuron degeneration in Amyotrophic Lateral Sclerosis.
Deep brain stimulation study is the first to successfully treat swallowing dysfunction in Parkinson’s disease.
Parkinson’s disease patients treated with low-frequency deep brain stimulation show significant improvements in swallowing dysfunction and freezing of gait over typical high-frequency treatment. The study, published in Neurology, provides a … Continue Reading Deep brain stimulation study is the first to successfully treat swallowing dysfunction in Parkinson’s disease.
Researchers at the University of California have shown that a micromotor fueled by stomach acid can take a bubble-powered ride inside a mouse. These tiny motors, each about one-fifth the … Continue Reading Stomach acid-powered nanobots get their first test in a living animal.
Neurorehabilitation helps hemaparetic stroke patients confronted with loss of motor skills on one side of their body, to recover some of their motor functions after a cerebrovascular accident. One of … Continue Reading Placebo-based neuroimaging study validates the use of non-invasive tDCS treatment for stroke.
Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis, or ALS, might damage muscle-controlling nerve cells in the brain earlier in the disease process than previously known, according to research … Continue Reading New point of origin identified for Amyotrophic Lateral Sclerosis (ALS).