Sepsis is the overreaction of the body’s immune system to infection capable of causing tissue damage, organ failure, and death.  Sepsis-causing bacteria secrete toxic molecules known as endotoxins which trigger immune cells shown to play a major role in inflammation.  These immune cells recognize the endotoxins as dangerous and produce proteins called pro-inflammatory cytokines.  These cytokines activate other macrophages to produce more cytokines, setting off a … Continue reading Engineered macrophage nanosponges could keep sepsis in check.