Obesity is a global health problem that poses a major risk factor for life-threatening diseases such as cardiovascular disease, cancer, and neurodegeneration. Recent studies have identified specific loci associated with … Continue Reading Study maps a molecular link between insulin-sensitivity and obesity.
Alzheimer’s disease is a devastating and progressive neurodegenerative disease affecting approximately 5.3 million people in the United States, including almost half of the population at 85 years and older. Microscopic hallmarks … Continue Reading New blood test detects early Alzheimer’s in large-scale study with unprecedented sensitivity.
Neurodegeneration in Alzheimer’s disease is thought to be caused by the abnormal behavior of amyloid-beta molecules, which are known to gather into tough fibril-like structures called amyloid plaques within patients’ … Continue Reading Human amyloid-beta shown to act as a powerful antibiotic in the brains of animal models.
Multiple sclerosis (MS) is a neurodegenerative disease in which the immune system attacks the myelin that protects nerve fibers, upsetting the flow of information between the brain and the body. … Continue Reading Human study identifies the genetic cause of familial multiple sclerosis.
The blood-brain barrier (BBB), a collection of cells and subcellular structures in the cerebrovascular wall that separates the circulating blood from the brain, is essential to keep brain tissue in … Continue Reading Leakages identified in the blood-brain barrier of patients with early Alzheimer’s disease.
Multiple Sclerosis (MS) is a neurological disease, characterised by demyelination and the onset of chronic, neurodegenerative damage of the central nervous system. Right now, its causes are unknown although various … Continue Reading Researchers identify a new gene involved in Multiple Sclerosis.
It is known that during disease, tau protein gets modified, changes its location in nerve cells and then aggregates. In healthy nerve cells, tau resides in a part of the … Continue Reading Previously unknown tau pathway leading to Alzheimer’s disease identified.
Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
Dementia is a common illness with an incidence that is rising as the aged population increases. A multitude of neurodegenerative illnesses have an associated dementia, including corticobasal degeneration, Creutzfeldt–Jakob disease, … Continue Reading Brain map researchers release first of it’s kind data on the aging human brain and traumatic brain injury.
A major problem of Alzheimer’s disease diagnosis is by the time the first clinical symptoms appear, massive irreversible damage to the brain has already occurred. At that point, symptomatic treatment … Continue Reading New infrared sensor extracts amlyloid-beta from blood for early detection of Alzheimer’s.
Dendritic spines are specialized protrusions responsible for receiving excitatory synaptic inputs, providing an important function in communication between neurons. The majority of excitatory synapses in the brain exist on dendritic … Continue Reading Novel molecule promotes the neuronal structures associated with memory to grow.
Spinal muscular atrophy is a debilitating disease that causes weakness and wasting of the muscles. The disease ranges in severity with patients experiencing different symptoms, from the inability to sit … Continue Reading Molecular mechanism underlying neurodegeneration in spinal muscular atrophy identified.
It is known that Parkinson’s disease, the second most common neurodegenerative disease, has genetic causes in 15% of cases. It has been shown that premature aging of dopaminergic neurons in the … Continue Reading Study shows how defective gene prematurely ages neurons in Parkinson’s disease.
After suffering a stroke, which is estimated to kill more than 6 million people annually, about three-quarters of patients exhibit some disability. It is known that most strokes occur when … Continue Reading Novel neuroprotector successfully reduces brain damage after stroke in preclinical studies.
It is known that Amyotrophic Lateral Sclerosis (ALS) gradually kills nerve cells in the brain and spinal cord. It is one of the most prevalent neuromuscular diseases, resulting in more … Continue Reading Study shows microglia has a direct role in the development of Lou Gehrig’s disease.
The human brain has a prodigious demand for energy, it uses 20 to 30% of the body’s energy budget. In the course of normal aging, in people with neurodegenerative diseases … Continue Reading Researchers use dietary supplement to re-energize aging brains in animal model.
Primary progressive aphasia (PPA) is a form of dementia characterized by degeneration of the language network. In the early stages, PPA is associated with a left-lateralized pattern of cortical atrophy … Continue Reading Neuroimaging can identify start and location of amyloid plaques in living brain.