In the brain, patterns of neural activity are perfectly balanced. The interplay between activating and inhibitory neurotransmitters ensures that the level of activity stays within the physiological range. Neuronal degeneration … Continue Reading Researchers begin to map neuroprotective pathway after epileptic seizure.
With Alzheimer’s disease medical professionals have to conduct costly brain imaging scans, and sometimes, invasive cerebral spinal fluid tests to rule out other diseases. Now, a new study from researchers … Continue Reading Human study identifies biomarker in blood for Alzheimer’s disease.
The incidence of HIV-associated dementia has declined dramatically since the introduction of potent combined antiretroviral therapy; however, milder forms of HIV-associated neurocognitive disorders (HAND) persist. Some 30 to 50 % of … Continue Reading Study shows how neural networks adapt to the presence of a toxic HIV protein.
It’s long been known that excess iron is found in the brains of patients with Parkinson’s disease (PD), an incurable neurodegenerative condition that affects motor function. However, the mechanism by … Continue Reading Researchers identify the neurogenetic basis of excess iron in Parkinson’s disease.
Alzheimer’s disease poses a health problem of pandemic proportions. It is estimated that by the year 2030 there will be greater than 60 million people worldwide with AD, and $375 … Continue Reading Newly identified role for ApoE explains its effects in Alzheimer’s.
Alzheimer’s disease is a progressive illness that is the leading cause of dementia and the sixth leading cause of death in the United States. There is no cure for the … Continue Reading Neuroimaging links two Alzheimer’s risk genes to brain atrophy, promising blood markers.
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons. This fatal disease is characterized by progressive muscular atrophy and doesn’t have an effective treatment. Patients with … Continue Reading Study provides first definitive evidence and description of protein clump toxicity in ALS.
Another year of growth for the Healthinnovations, many great breakthroughs, with previously immature technologies and disciplines coming into their own, as crucial parts of global innovation. For instance, biomarkers have … Continue Reading The Top Ten Healthinnovations of 2015.
Obesity increases risk of age-related cognitive decline and is accompanied by peripheral inflammation. Studies in rodent models of obesity have demonstrated that impaired hippocampal function correlates with microglial activation, however, … Continue Reading Study shows obesity causes microglia to start eating neural connections.
Cerebral blood flow is rigorously regulated by various mechanisms to safeguard the match between cerebral metabolic demand and supply. The question of how a change in heart health affects cerebral … Continue Reading Large-scale human study identifies link between early-stage heart and brain disease.
The standard model of natural selection predicts that once the age of reproduction ends, individuals die. That’s because selection early in life strongly favors variants that benefit reproductive success, even … Continue Reading Study identifies gene variants which protect older adults from neurodegeneration.
Huntington’s disease is an inherited disorder that damages nerve cells and causes parts of the brain to deteriorate, leading to uncontrolled movements and cognitive problems. There is no way to … Continue Reading Study identifies previously unknown proteins in Huntington’s disease pathology.
Aging is a major risk factor for many human diseases, and in vitro generation of human neurons is an attractive approach for modeling aging-related brain disorders. While aggressive familial early … Continue Reading New technique enables researchers to grow old human brain cells for the first time.
An estimated seven to ten million people worldwide are living with Parkinson’s disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. … Continue Reading Study first to link immunogenetics to non-familial Parkinson’s disease.
Differences in the size and structure of certain brain areas have been found in some adults diagnosed with schizophrenia. Early findings came from the discovery of enlarged ventricles in people … Continue Reading Neuroimaging matches specific schizophrenia behaviour to the brain’s anatomy.
Cognitive function is known to change during normal aging and in age-related disease such as Alzheimer’s disease. Although the exact cause for age-related cognitive decline is not clear, recent studies … Continue Reading Researchers combat memory loss by enhancing brain function in animal model.