The development of neural connectivity is essential for brain function, and disruption of this process is associated with autism spectrum disorder (ASD). Now, a study from researchers led by McMaster … Continue Reading Study identifies autism gene which regulates dendrite development to slow down brain communication.
Intracranial aneurysms are a potentially life threatening neurological condition responsible for approximately 500,000 deaths worldwide per year, half of which occur in people less than 50 years of age. They … Continue Reading Gene associated with intracranial aneurysm in French-Canadian population identified.
It is known that Alzheimer’s disease is more common in African-Americans than Caucasians, however, the Alzheimer’s disease genetic risk profile for African-Americans is poorly understood. While more than 20 genes have … Continue Reading Study identifies 2 new genes responsible for Alzheimer’s disease among African-Americans.
Alzheimer’s disease is a neurodegenerative disorder characterized by progressive memory loss and cognitive dysfunction. It affects more than 30 million people worldwide, including an estimated 5.4 million Americans. One in … Continue Reading Dysfunction in neuronal transport mechanism linked to Alzheimer’s disease.
Adult brain cancers are almost always universally fatal, due in part to the biochemical composition of the central nervous system and the blood-brain barrier, which selectively and protectively limits the … Continue Reading Animal study shows depriving deadly brain cancer of cholesterol kills tumour cells.
A significant milestone in the evolution of the mammalian brain is the emergence of the corpus callosum, which is exclusively present in placental mammals. This commissure forms the largest axon … Continue Reading Neuroimaging shows that astrocytes are responsible for joining the 2 halves of the brain together.
The onset of ALS, also known as Lou Gehrig’s disease, is marked by the gradual degradation and eventual death of neuronal axons, the slender projections on nerve cells which transmit … Continue Reading Researchers identify the key instigator of neuron damage in sporadic and inherited ALS.
The children of traumatized people have long been known to be at increased risk for post-traumatic stress disorder (PTSD). However, there are very few opportunities to examine biologic alterations in … Continue Reading Trauma’s inherited epigenetic fingerprint observed in children of Holocaust survivors.
Genetic variation accounts for a major proportion of the liability to autism spectrum disorder (ASD). Now, a study from led by researchers at UCLA shows that in families with multiple … Continue Reading Largest study of its kind sheds new light on the complex genetics of autism.
It is known that nerves in the central nervous system of adult mammals do not usually regenerate when injured. However, the granule cell, a nerve cell located in the cerebellum, … Continue Reading Key molecule in the elusive regeneration of cerebellum synaptic connections identified.
For decades, scientists have known that people with two copies of a gene called apolipoprotein E4, or ApoE4, are much more likely to have Alzheimer’s disease at age 65 than … Continue Reading Study shows why people with the ApoE4 gene are more susceptible to Alzheimer’s disease.
Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.
It is known that genetics plays a role in obesity, with genes directly causing obesity in disorders such as Bardet-Biedl syndrome and Prader-Willi syndrome. However, genes and behaviour may both … Continue Reading Human study shows ‘aggressive drunk’ gene may protect carriers from obesity and associated risks.
Charcot-Marie-Tooth Disease (CMT) is a family of inherited disorders of the peripheral nervous system, affecting approximately one in 2,500 Americans. Its most common iteration, CMT1, comes in many forms, most … Continue Reading Researchers identify previously unknown genetic cause of inherited neuropathy.
A neuron is an electrically excitable cell that processes and transmits information through electrical and chemical signals in the brain. These signals between neurons occur via synapses, which connect to … Continue Reading Study maps neurogenetics of dendritic growth and formation.
Approximately 16% of adults in the United States report drug use, however, not everyone who experiments with drugs becomes an addict. Environmental and societal factors play a role in addiction … Continue Reading First ever study identifies epigenetic markers that influence addiction in animal model.