Worldwide, more than 20% of persons over the age of 85 suffer from Alzheimer’s disease. Deposits of beta-amyloid (Aβ) peptide represent an important target for research into Alzheimer’s disease. These … Continue Reading Researchers take a step towards utilising the brain’s microglia to fight Alzheimer’s disease.
Air pollution is a serious public health issue and exposures to concentrations of air pollutants at or above the current standards has been linked to neuroinflammation and neurodegeneration. In the … Continue Reading Study shows that air pollution has detrimental impact on Alzheimer’s risk gene.
The need for a new approach to treat Alzheimer’s is an urgent priority for governments across the globe. It is the most common age-related dementia, and the number of people … Continue Reading Gamechanging human study identifies 3 distinct subtypes of Alzheimer’s disease.
Alzheimer’s is the most common form of dementia, causing problems with memory, thinking and behaviour. Symptoms usually develop slowly and get worse over time as it is a progressive disease; … Continue Reading Largest ever human trial shows resveratrol impacts Alzheimer’s biomarker.
Examining post-mortem tissue from the brains of people with Alzheimer’s disease, Stanford University researchers state they have identified what appear to be iron-containing microglia, specialized scavenger cells that sometimes become … Continue Reading A human study identifies region specific iron-containing microglia in Alzheimer’s brains.
A new neuroimaging study has shown that in just two years people with type 2 diabetes experienced negative changes in their ability to regulate blood flow in the brain This … Continue Reading Long-term human study shows detrimental effect diabetes has on brain plasticity.
Through studying brain scans and cerebrospinal fluid of healthy adults researchers at Washington University have shown that changes in key biomarkers of Alzheimer’s disease during midlife can help identify those who … Continue Reading First ever large-scale human study validates multiple biomarkers for Alzheimer’s disease.
Researchers at the University of Kentucky have completed a study that revealed differences in the way neuroinflammation, considered a key component of Alzheimer’s disease, is expressed in different subsets of … Continue Reading Study finds Alzheimer’s disease presents differently in patients with Down syndrome.
Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain … Continue Reading Researchers link microglia activation triggered by chronic pain to anxiety and depression.
Scientists have long suspected that neuroinflammation caused by a reactive immune system could be tripping off the neurodegeneration seen in certain dementias, multiple sclerosis, and other deadly diseases of the … Continue Reading Immune response in the human brain accurately measured for the first time ever.
A drug that could halt the progression of multiple sclerosis may soon be developed thanks to a discovery by a team at the CHUM Research Centre and the University of … Continue Reading New treatment blocks progression of mutliple sclerosis in animal model.
Researchers have found that an antiviral compound may protect the brain from invading pathogens. Studying West Nile virus infection in mice, researchers at Washington University showed that interferon-lambda tightens the … Continue Reading Researchers ‘block’ the West Nile virus out of the brain by tightening the blood-brain barrier.
The mission of neural stem cells located in the hippocampus, one of the main regions of the brain, is to generate new neurons during the adult life of mammals, including … Continue Reading Researchers validate microglia role in reducing neurogenesis due to epileptic seizures.
New research by researchers at the University of Massachusetts suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting … Continue Reading Researchers identify the role of microglia in Rett syndrome.
Despite symptom-stifling anti-retroviral drugs, as many as half of all patients living with HIV experience neurological damage tied to chronic inflammation in the brain fueled by the body’s own immune … Continue Reading Study discovers the role of microglia in HIV-related neurological damage.
Researchers at the University of North Carolina have used exosomes, tiny bubbles of protein and fat produced naturally by cells, to bypass the body’s defenses and deliver a potent antioxidant … Continue Reading Researchers utilize natural exosomes to deliver Parkinson’s treatment directly to brain.