Angiogenesis, the growth of new blood vessels from pre-existing ones, is required for wound healing, menstruation, embryogenesis and various pathological conditions including tumour growth. Macrophages, key cells of the innate … Continue Reading Immune cells shown to facilitate tumour growth by forming primitive vascular channels.
In oncology, the Warburg effect is the observation that that the driver of tumourigenesis is an insufficient cellular respiration caused by insult to mitochondria. It postulates that most cancer cells, … Continue Reading Study uncovers vital Warburg effect pathway in brain tumour formation and metabolism.
It has been established that not all cancer cells are equally aggressive, most can be neutralised with radiation and chemotherapy. Now, a study from researchers at Lund University shows that … Continue Reading Study shows cancer cells can become aggressive and metastasize by storing fat cells.
A mammals’ body temperature is usually constant, however, when exposed to cold their body temperature drops by few degrees before slowly rising almost back to normal. This adaptive mechanism is … Continue Reading Study shows how gut microbiota regulates weight loss & good fat in the cold.
It has been shown that patterns of poor nutritional intake may exacerbate the elevated morbidity experienced by cancer survivors. While most cancer patients in the United States are motivated to … Continue Reading Large-scale study investigates the diet quality of cancer survivors.
There is well-established evidence that free radicals can cause cancer so researchers had assumed that antioxidants, which destroy them, provide protection against the disease. Found in many nutritional supplements, antioxidants … Continue Reading Study shows antioxidants speed-up the metastasis of malignant melanoma.
The mammalian target of rapamycin, a drug originally developed to prevent immunosuppression, is mTOR. mTOR is one of the most critical proteins in the control of cell proliferation, including cancer. … Continue Reading Study identifies mTOR pathway that controls cancer proliferation via nutrients.
National Institutes of Health (NIH) researchers and their colleagues have developed a ‘placenta-on-a-chip’ to study the inner workings of the human placenta and its role in pregnancy. The device was … Continue Reading Researchers successfully develop placenta-on-a-chip which mirrors what occurs in the human body.
Long non-coding RNAs (lncRNA) are unusual in that they don’t encode proteins like normal RNA. Yet they do play a role in regulating cellular functions and interest cancer researchers. Now, … Continue Reading Researchers identify long non-coding RNA which modulates colorectal cancer metabolism.