When exposed to cold, clusters of cells within the body’s white fat become beige, a colour change which reflects the creation of more energy-producing mitochondria, cellular components that enable cells … Continue Reading Study shows that fat cells which amplify nerve signals in response to cold also affect blood sugar.
The decision to engage in food-seeking behaviour depends on homeostatic signals relating to energy balance and the presence of competing motivational drives, as well as learned brain cues signaling food … Continue Reading Neuroimaging shows the effect of hunger on the brain’s response to food cues.
Generally, researchers divide the human immune system into two parts. One part, called the innate immune system, allows for immediate and direct recognition of invading bacteria. It prompts immune cells … Continue Reading Study identifies previously unknown mechanism of the immune system.
About 8% of Americans have type 2 diabetes, and another 25% of the population is at risk because of obesity. Type 2 diabetes is a lifelong disease that represents an … Continue Reading Study identifies new pathway in insulin resistance.
The rapid rise in obesity and associated spread of type 2 diabetes represent an enormous challenge for society, with no efficient and safe medicines to prevent or stop this development … Continue Reading Astrocytes shown to control sugar in the brain, as well as neurons.
It is known that genetics plays a role in obesity, with genes directly causing obesity in disorders such as Bardet-Biedl syndrome and Prader-Willi syndrome. However, genes and behaviour may both … Continue Reading Human study shows ‘aggressive drunk’ gene may protect carriers from obesity and associated risks.
Understanding the integrative role of the central nervous system in the prevalence of obesity and obesity-related diseases is of great importance. It has been hypothesized that flexibility of food reward–related … Continue Reading Neuroimaging shows that response to food cues differ in severely obese women.
Obesity is a global health problem that poses a major risk factor for life-threatening diseases such as cardiovascular disease, cancer, and neurodegeneration. Recent studies have identified specific loci associated with … Continue Reading Study maps a molecular link between insulin-sensitivity and obesity.
Body mass index (BMI) is an important risk factor for breast cancer development and invasiveness. After menopause, women have an increased risk of developing breast cancer with increased BMI, while … Continue Reading New MRI technique links saturated fats to breast cancer in postmenopausal women.
It has been established that not all cancer cells are equally aggressive, most can be neutralised with radiation and chemotherapy. Now, a study from researchers at Lund University shows that … Continue Reading Study shows cancer cells can become aggressive and metastasize by storing fat cells.
Obesity has become a major health threat, affecting more than half a billion people worldwide in 2014. In particular, obesity increases the risk for insulin resistance, hypertension, coronary heart disease … Continue Reading Epigenetic modification which raises obesity risk and predicts fatty liver identified.
Twenty-years ago there was a big step forward in the understanding of obesity when researchers discovered that a person’s appetite is controlled by a key molecule called leptin. Leptin is … Continue Reading Glia brain cells implicated in appetite control.
Worldwide obesity has more than doubled since 1980. In 2014, there were over 600 million people classified as obese, making up 13% of the global population. Researchers have long known … Continue Reading Researchers stimulate brown-fat in animals to improve weight-management and glucose control.
With type 1 diabetes too much glucose and fat circulating in the blood help make cardiovascular disease the leading cause of death and disability in people with the disease. While … Continue Reading New pathway and potential treatment identified for unhealthy levels of fat in type 1 diabetes.
The autonomic nervous system, made up of sympathetic and parasympathetic branches, is known to regulate blood glucose levels by directly controlling insulin secretion by the pancreas. Insulin secretion and blood … Continue Reading Hormone inhibits neuronal connections between the brain and pancreas in neurodevelopment.
The molecular intricacies of hunger and satiety, pivotal for understanding metabolic disorders and the problem of obesity, are not yet fully understood by scientists. How much a person eats and … Continue Reading Protein responsible for regulating feeding behaviour in the brain identified.