Pain is an unpleasant sensory and emotional experience caused by stimulating nerve receptors contained within tissue damaged by trauma. Usually pain dissipates once the traumatic stimulus is removed and the … Continue Reading Study claims to have found the center of pain in the brain.
Chronic pain is defined as any persistent pain which lasts more than 3 months, with research indicting over 85% of patients suffering from chronic pain are affected by severe depression, … Continue Reading Molecular link between chronic pain and depression identified.
An out-of-control pandemic still growing after many decades, chronic pain is the most common reason for physician consultation in most developed countries around the world, with almost one in five … Continue Reading Previously unknown sensory organ identified.
Approximately half the adult population in the United States is suffering from back or neck pain whose treatment and care costs result in an estimated 195 billion USD a year. … Continue Reading Spinal discs made of engineered living tissue implanted in large animal model.
According to human anatomy, the ligaments in the ankle are grouped by two ligament complexes, namely the lateral collateral ligament and the medial collateral ligament. The ankle lateral collateral ligament … Continue Reading Researchers discover a new anatomic structure in the ankle.
Pain hypersensitivity can spread to unaffected body regions immediately surrounding the initial insult. Sometimes it can even spread to the opposite site of the body or to large body areas … Continue Reading Pain-initiating function of glial cells identified for the first time.
Neuropathic pain is deﬁned as pain initiated or caused by a primary lesion or dysfunction in the nervous system. Chronic neuropathic leg pain is the most common form of neuropathic … Continue Reading Neuroimaging shows that spinal cord stimulation reduces emotional aspect of chronic pain.
In the treatment of pain, a common course is to treat patients with opioid medications, these medications show limited effectiveness for neuropathic pain and come with safety and addiction issues. … Continue Reading Researchers map how antidepressants lessen neuropathic pain.
Every person wants to know what he or she can do to lower their risk of breast cancer. Some of the factors associated with breast cancer, such as sex, age … Continue Reading First ever human study validates anti-stress hormone as an indicator for breast cancer risk.
Diabetic neuropathy is a condition in which perpetually high blood sugar causes nerve damage, resulting in a myriad of symptoms such as numbness, reduced ability to detect painful stimuli, muscle … Continue Reading Stem cell injections improve diabetic neuropathy in animal models.
Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain … Continue Reading Researchers link microglia activation triggered by chronic pain to anxiety and depression.
A new literature review study from researchers at the University of Tel Aviv has found that people with dementia and other forms of cognitive impairment have altered responses to pain, with … Continue Reading Lit review study finds altered pain processing in patients with cognitive impairment.
A chemical in the brain typically associated with cognition, movement and reward-motivation behaviour, among others, may also play a role in promoting chronic pain, according to new research from researchers … Continue Reading Researchers map dopamine based chronic-pain pathway in the spinal cord and brain.
Researchers successfully implant and control light-sensitive opioid receptors in mice via optogenetics.
Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp … Continue Reading Researchers successfully implant and control light-sensitive opioid receptors in mice via optogenetics.
A protein that normally fosters tissue repair instead acts to inhibit healing when sugar levels are high, according to a study in The Journal of Cell Biology. The data findings … Continue Reading Researchers map epigenetic cause of slowed diabetic wound healing.
In a new study from Saint Louis University, researchers discovered that drugs targeting the A3 adenosine receptor can turn off pain signals in the spinal cord to provide relief from … Continue Reading Researchers use A3 adenosine receptors to activate ‘off signals’ for chronic pain.