A crucial part of our defence against disease, the composition and diversity of the gut microbiome can even affect how cancer immunotherapy works. However, little research has focused on the … Continue Reading The tumour microbiome influences immune response and survival in pancreatic cancer.
Researchers have long explored ways to transplant pancreatic islets to treat type I diabetes in the long term to eliminate the need for continuous glucose monitoring and insulin injections. However, … Continue Reading Tiny drug-delivering capsules could sustain transplanted insulin-producing cells.
Pancreatic cancer is a devastating disease, with a death rate close to the incidence rate. Because more than 90% of pancreatic cancer cases are diagnosed at the metastatic stage, when … Continue Reading Early indicators of pancreatic cancer identified in precision medicine study.
Glucose-stimulated insulin secretion (GSIS) in pancreatic beta cells maintains glucose homeostasis and prevents diabetes. Despite decades of studies, knowledge about what controls the precise amount of insulin release on a … Continue Reading Researchers identify microtubule mechanism and role in insulin secretion.
Ten million Canadians are living with diabetes or pre-diabetes. The Canadian Diabetes Association reports that more than 20 Canadians are newly diagnosed with the disease every hour of every day. … Continue Reading New mitochondria-based insulin amplifier pathway identified in T2 diabetes.
To combat pathogens, the immune system has developed various mechanisms to detect, defend against and even destroy micro-organisms that are harmful to the body. This includes antimicrobial peptides and natural … Continue Reading International team identifies bacteria which protect against type 1 diabetes.
Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been … Continue Reading New diagnostic identifies mitochondria dysfunction in Type 2 diabetes.
In a breakthrough in the understanding of how cancer does its deadly work, researchers at the University of Virginia have shown that many cancers, including nearly all pancreatic cancers, enslave … Continue Reading Researchers show how common cancers hijack and deform mitochondrial fission.
T1 diabetes cure close as researchers devise method to repel immune cells in pancreatic islets transplant.
An approach developed by Massachusetts General Hospital (MGH) researchers may provide a solution to the limitations that have kept pancreatic islet transplantation from meeting its promise as a cure for … Continue Reading T1 diabetes cure close as researchers devise method to repel immune cells in pancreatic islets transplant.
Existing cancer therapies are geared toward killing tumour cells, but Johns Hopkins researchers propose a different strategy, subtly hardening cancer cells to prevent them from invading new areas of the … Continue Reading New strategy sees therapy ‘stiffening’ cancer cells and limiting mobility.
UT Southwestern Medical Center researchers have demonstrated that whole-genome sequencing can be used to identify patients’ risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, diagnosis, … Continue Reading Researchers confirm whole-genome sequencing can identify cancer-related mutations and risk.
Many recent studies showed that calorie restrictions reduce the incidence of cancer, whereas high-calorie diets cause obesity and diabetes, both of which increase the risk of developing cancers. However, tumour … Continue Reading A change of diet to unmask cancer vulnerabilities and reduce cancer risk.