An analysis of five families has revealed a previously unknown genetic immunodeficiency, says an international team led by researchers from Boston Children’s Hospital. The condition, linked to mutations in a … Continue Reading International team discovers previously unknown genetic immunodeficiency.
Clostridium difficile is a dangerous intestinal bacterium that can cause severe diarrhoea and life-threatening intestinal infections after long-term treatment with antibiotics. Bacteria such as this are becoming increasingly resistant to … Continue Reading The molecular docking site of the intestinal pathogen C. difficile has been identified.
At its annual assembly in Geneva last week, the World Health Organization approved a radical and far-reaching plan to slow the rapid, extensive spread of antibiotic resistance around the world. … Continue Reading New bacteriophage precision medicine reverses antibiotic resistance in bacteria.
Tuberculosis is caused by the bacterium Mycobacterium tuberculosis and it affects over 12 million people globally. When the bacterium infects a person, the body’s immune response is critical to how … Continue Reading Researchers identify how tuberculosis uses precision medicine to trick the immune system.
A study by researchers at UT Southwestern Medical Center has identified how an enzyme involved in protecting the body from pathogens senses Mycobacterium tuberculosis (TB), a bacterial pathogen that infects … Continue Reading Multiple studies show that immunity enzyme defends against tuberculosis infection.
New technology developed by Howard Hughes Medical Institute (HHMI) and Brigham and Women’s Hospital researchers makes it possible to test for current and past infections with any known human virus by … Continue Reading New bacteriophage-based assay gives a person’s whole viral infection history in a drop of blood.
Researchers at the University of Bonn and the German Center for Infection Research (DZIF) have discovered two new groups of viruses within the Bunyavirus family in the tropical forest of … Continue Reading Researchers have discovered two new groups of viruses.
Researchers have found that an antiviral compound may protect the brain from invading pathogens. Studying West Nile virus infection in mice, researchers at Washington University showed that interferon-lambda tightens the … Continue Reading Researchers ‘block’ the West Nile virus out of the brain by tightening the blood-brain barrier.
Nanoengineers at the University of California, San Diego have developed a gel filled with toxin-absorbing nanosponges that could lead to an effective treatment for skin and wound infections caused by … Continue Reading Study shows nanosponge cleans up MRSA infections without the use of antibiotics.
The bacteria that sneak past the brain’s defenses to cause deadly bacterial meningitis are clever adversaries. Bacteria use various molecular tricks bacteria use to convince their host that they are … Continue Reading Study identifies ‘molecular trick’ used by bacteria to bypass the blood-brain barrier.
Investigators at the Stanford University have identified a pattern of gene activity that could help scientists create a blood test for quickly and accurately detecting whether patients are experiencing a … Continue Reading Researchers identify the genetic signature for early, accurate sepsis diagnosis.
Despite symptom-stifling anti-retroviral drugs, as many as half of all patients living with HIV experience neurological damage tied to chronic inflammation in the brain fueled by the body’s own immune … Continue Reading Study discovers the role of microglia in HIV-related neurological damage.
Live Ebola virus can persist within the eyes for months after a patient recovers from acute Ebola viral disease (EVD), according to a case report from researchers at Emory University. … Continue Reading Ebola virus can persist for months within survivors’ eyes.
A protein that normally fosters tissue repair instead acts to inhibit healing when sugar levels are high, according to a study in The Journal of Cell Biology. The data findings … Continue Reading Researchers map epigenetic cause of slowed diabetic wound healing.
Tick-borne diseases are a major public health problem around the world. Ticks carry and transmit a variety of microbes that cause disease. These illnesses, which include Lyme disease, Rocky Mountain … Continue Reading Researchers discover never-before-seen tick-borne disease.
About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. Now, researchers from Tulane National Primate Research Center and Louisiana … Continue Reading Researchers map neuroinflammation and nervous system manifestations of Lyme disease.