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Researchers image the epigenetics of the human brain for the first time ever.

Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge … Continue Reading Researchers image the epigenetics of the human brain for the first time ever.

Neuroimaging can identify start and location of amyloid plaques in living brain.

Primary progressive aphasia (PPA) is a form of dementia characterized by degeneration of the language network.  In the early stages, PPA is associated with a left-lateralized pattern of cortical atrophy … Continue Reading Neuroimaging can identify start and location of amyloid plaques in living brain.

Neuroimaging shows genetics and environment affect different regions of brain.

It is known that glucose is an essential fuel for brain energy metabolism as well as oxygen.  Functional activation of neurons is normally associated with increases in the local cerebral … Continue Reading Neuroimaging shows genetics and environment affect different regions of brain.

Study validates beta amyloid as cause of dementia in both Alzheimer’s and Down syndrome.

More than five million Americans are living with Alzheimer’s disease (AD). Of them, 400,000 also have Down syndrome. People with Down syndrome (DS) represent the world’s largest population of predetermined … Continue Reading Study validates beta amyloid as cause of dementia in both Alzheimer’s and Down syndrome.

First ever large-scale human study validates multiple biomarkers for Alzheimer’s disease.

Through studying brain scans and cerebrospinal fluid of healthy adults researchers at Washington University have shown that changes in key biomarkers of Alzheimer’s disease during midlife can help identify those who … Continue Reading First ever large-scale human study validates multiple biomarkers for Alzheimer’s disease.

Neuroimaging study identifies characteristic pattern of protein deposits in brains of retired athletes who suffered concussions.

A new UCLA study takes another step toward the early understanding of a degenerative brain condition called chronic traumatic encephalopathy, or CTE, which affects athletes in contact sports who are … Continue Reading Neuroimaging study identifies characteristic pattern of protein deposits in brains of retired athletes who suffered concussions.

Neuroimaging study finds first evidence of neuroinflammation in brains of chronic pain patients.

A new study from Massachusetts General Hospital (MGH) researchers has found, for the first time, evidence of neuroinflammation in key regions of the brains of patients with chronic pain. By … Continue Reading Neuroimaging study finds first evidence of neuroinflammation in brains of chronic pain patients.