A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behaviour independent of, and ahead of, its other antidepressant effects, in a National Institutes of Health trial. Within 40 minutes after a single infusion of ketamine, treatment-resistant depressed bipolar disorder patients experienced a reversal of a key symptom, loss of interest in pleasurable activities, which lasted up to 14 days. Brain scans traced the agent’s … Continue reading Rapid-acting agent restores pleasure-seeking in bipolar neuroimaging trial participants.