Dopamine deficiency in the basal ganglia is known to cause severe motor dysfunctions such as slowness of movement, or bradykinesia, as seen in Parkinson’s disease. Dopamine binds D1 and D2 receptors … Continue Reading Study identifies the cause of slowness of movement in Parkinson’s disease.
Glutamate is an amino acid with very different functions. In the pancreas, it modulates the activity of the pancreatic ß-cells responsible for insulin production, whereas in the brain it is … Continue Reading Study verifies long-standing hypothesis that glutamate is brain’s energy-source.
In the mammalian central nervous system, neurons receive inhibitory synaptic inputs from gamma-aminobutyric acid (GABA)ergic interneurons and excitatory inputs from glutamatergic neurons. Evidence suggests that the dysfunction of appropriate GABAergic … Continue Reading Study implicates two genes in the cause of schizophrenia, vital for signalling balance.
Human multitasking is the apparent performance by an individual of handling more than one task, or activity, at the same time. Studies have shown that some people can be trained … Continue Reading Neuroimaging study maps the neural basis of multitasking.
Antidepressants are recommended as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy. Experts recommend against their … Continue Reading Study maps structural brain changes caused by antidepressants.
Synaptic mitochondria are thought to be critical in supporting neuronal energy requirements at the synapse, and bioenergetic failure at the synapse may impair neural transmission and contribute to neurodegeneration. However, … Continue Reading Researchers link impaired mitochondria and a loss of ATP to neurodegeneration.
For several decades, addiction has come to be viewed as a disorder of the dopamine neurotransmitter system; however, this view has not led to new treatments. Numerous studies suggest that … Continue Reading Researchers identify specific neuron-type responsible for alcoholism.
Researchers identify protein in the brain which inhibits key enzyme implicated in Alzheimer’s disease.
The need for a new approach to treatment of Alzheimer’s disease is urgent. Alzheimer’s is the most common age-related dementia and the number of cases in the United States is … Continue Reading Researchers identify protein in the brain which inhibits key enzyme implicated in Alzheimer’s disease.
Many genes responsible for the creation of synaptic proteins have previously shown to be strongly linked to schizophrenia and other brain disorders, however, until now the reasons have not been … Continue Reading Researchers identify schizophrenia’s ‘master-key’ gene.
A team from the University of South Carolina have been studying one of the fundamental biomolecules contributing to human addiction, the mu-opioid receptor. It’s a protein in the human body … Continue Reading Researchers begin to map the neurogenetics of susceptibility in addiction.
Some common themes are beginning to emerge from research on structural and functional brain connectivity in autism spectrum disorders (ASD). However, much more work will be needed to learn how … Continue Reading Multiple neuroimaging studies point to brain connectivity changes in autism.
A new neuroimaging study has shown that in just two years people with type 2 diabetes experienced negative changes in their ability to regulate blood flow in the brain This … Continue Reading Long-term human study shows detrimental effect diabetes has on brain plasticity.
In the first study of its kind researchers from UCLA and the University of Leicester found that neurons in a specific brain region play a key role in rapidly forming … Continue Reading First ever study records memory being encoded in individual neurons.
Speech is produced in the human cerebral cortex and previous studies have shown that the brain waves associated with speech processes can be directly recorded with electrodes located on the … Continue Reading Researchers develop world’s first thought-based ‘brain-to-text’ system.
A new study from researchers at Stanford University found that synchronized physiological interactions between remote regional brain neuron networks have genetic underpinnings. The research was performed at Stanford but was … Continue Reading Researchers begin to map the neurogenetics of neural network theory.
A team of researchers from the University of Maryland have developed a new imaging technique that can identify the specific changes in neural communication as a result of mild traumatic brain … Continue Reading New imaging technique pinpoints changes in brain connectivity following mTBI.