Critically, the growth of children’s bones depends on growth plates situated close to the end of all long bones in the body. These plates are narrow discs of cartilage providing … Continue Reading New mechanism of bone growth uncovered.
Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. One major task en route to the clinic is to generate standardized good manufacturing practice (GMP)-grade human-pluripotent … Continue Reading Breakthrough in the production of dopamine neurons for Parkinson’s disease.
Demyelinating diseases, such as multiple sclerosis and leukodystrophy, are characterized by damage to the protective myelin sheath that surrounds the axons of neurons. This demyelination can be caused by an … Continue Reading Cell therapy successfully promotes axon remyelination in an animal model.
Compared to other mammals, humans have the largest cerebral cortex. A sheet of brain cells that folds in on itself multiple times in order to fit inside the skull, the … Continue Reading Researchers identify and map a previously unknown gene critical for human brain development.
Brazil is in the midst of an unprecedented epidemic of Zika virus (ZIKV), a flavivirus that is transmitted by mosquitoes and sexually, which was first detected in the country in … Continue Reading New research provides mechanism and evidence of how Zika virus causes microcephaly in newborns.
In a cancerous breast, researchers have seen the problems with the various components of breast tissue and could not fully explain why they happened. The tissue, called the stroma, includes … Continue Reading Human study identifies new gene as cause and early indicator of breast cancer.
The human brain is home to many different types of neurons with their own genetic signature to define their function. These neurons are derived from progenitor cells, which are specialized … Continue Reading The ‘neuronal big bang’ is visualised for the first time.
Irreversible degeneration of the cardiac conduction system is a common disease with high rates of mortality. While electronic pacemakers provide effective treatment, alternative approaches are needed with long-term implanted hardware … Continue Reading Extensive lit review performed on harnessing stem cells to generate biological pacemakers.
In human blood formation, everything begins with the stem cell, which is the executive decision-maker quickly driving the process that replenishes blood at a daily rate that exceeds 300 billion … Continue Reading Researchers redefine how blood is made.
Heart regeneration a step closer as researchers identify progenitor cell exclusively for heart muscle.
Future therapies for failing hearts are likely to include stem-like cells and associated growth factors that regenerate heart muscle. Now, researchers from the University of Pennsylvania have just taken an … Continue Reading Heart regeneration a step closer as researchers identify progenitor cell exclusively for heart muscle.
University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that … Continue Reading Reseachers identify and map progenitor cells for blood and immune cell production.
A team of Massachusetts General Hospital (MGH) investigators have made the first steps towards development of bioartificial replacement limbs suitable for transplantation. In their report the researchers describe using an … Continue Reading Researchers successfully bioengineer whole forelimb, transplant and reanimate it in animal model.
Newborn neurons generated from neural progenitor cells in a brain region called the hippocampus play an important role in learning and memory in adults. However, the molecular mechanisms that control … Continue Reading Researchers map epigenetic pathway of neurogenesis in the hippocampus.
An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there … Continue Reading Stem cell injection reverses vision loss due to age-related macular degeneration in animal model.
Healthy bone is continuously involved in a dynamic process that includes bone deposition and bone resorption. However, when a person has cancer that spreads to the bone and bone marrow, … Continue Reading Researchers identify new role for cytokine VEGFA in the metastasis of neuroblastoma.
Researchers at the Stanford University have discovered that when a certain aggressive leukemia is causing havoc in the body, the solution may be to force the cancer cells to grow … Continue Reading Researchers engineer a ‘cancer differentiation therapy’ for leukemia.