In human blood formation, everything begins with the stem cell, which is the executive decision-maker quickly driving the process that replenishes blood at a daily rate that exceeds 300 billion … Continue Reading Researchers redefine how blood is made.
Intracardiac septal defects are the most common congenital defects in the young. The gold standard treatment is suture-based surgical closure, requiring cardiopulmonary bypass, which can increase the risk of pump-related … Continue Reading Catheter can fix holes in the heart without invasive surgery.
As humans grow older, they lose strength and muscle mass. Skeletal muscle weakness and atrophy are among the most pervasive and disruptive effects of aging. In nearly all people, even … Continue Reading Researchers identify precise cause of muscle weakness and loss due to aging.
Of all the body’s major organs the liver has the highest capacity to regenerate and that’s why many liver diseases, including cirrhosis and hepatitis, can often be cured by transplanting … Continue Reading Researchers discover cells that regenerate the liver without forming tumours.
Studying telomeres, the structures that protect the ends of chromosomes, has become a key issue in biology. In recent years, not only has their relation to aging been confirmed; defective … Continue Reading Extensive review maps all known diseases caused by defective telomeres.
Chronic spinal cord injury (SCI) is a formidable hurdle that prevents a large number of injured axons from crossing the lesion, particularly the corticospinal tract (CST). Patients inflicted with SCI … Continue Reading Researchers identify precision medicine to regenerate corticospinal tract axons.
Heart regeneration a step closer as researchers identify progenitor cell exclusively for heart muscle.
Future therapies for failing hearts are likely to include stem-like cells and associated growth factors that regenerate heart muscle. Now, researchers from the University of Pennsylvania have just taken an … Continue Reading Heart regeneration a step closer as researchers identify progenitor cell exclusively for heart muscle.
Diabetic neuropathy is a condition in which perpetually high blood sugar causes nerve damage, resulting in a myriad of symptoms such as numbness, reduced ability to detect painful stimuli, muscle … Continue Reading Stem cell injections improve diabetic neuropathy in animal models.
University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that … Continue Reading Reseachers identify and map progenitor cells for blood and immune cell production.
The human heart makes precious few new cells but manages to generate billions of life-sustaining beats as it grows old. Now research conducted in fruit flies, rats and monkeys by … Continue Reading Researchers identify protein that protects heart function into old age.
A research group from Helmholtz Zentrum München has developed an assay whereby mini-breasts in-a-dish can be grown, with cultured human breast epithelial cells rebuilt into the three-dimensional tissue architecture of the … Continue Reading Researchers grow mini breast-in-a-dish, provide breakthrough in breast cancer proliferation.
Researchers have long wondered what causes people to lose muscle strength as they age and how exercise can prevent it from happening. Now, McMaster University researchers have discovered a key … Continue Reading Researchers identify protein required to maintain muscle mass and strength during aging.
A team of Massachusetts General Hospital (MGH) investigators have made the first steps towards development of bioartificial replacement limbs suitable for transplantation. In their report the researchers describe using an … Continue Reading Researchers successfully bioengineer whole forelimb, transplant and reanimate it in animal model.
Scientists from the Institut Pasteur, CNRS, Institut Gustave Roussy and CEA, have succeeded in restoring normal activity in cells isolated from patients with the premature aging disease Cockayne syndrome. They … Continue Reading Researchers identify and correct premature aging in diseased cells.
A molecular switch that seems to be essential for embryonic heart cells to grow into more mature, adult-like heart cells has been discovered by researchers at University of Washington. The … Continue Reading Researchers identify the molecular switch that promotes heart cell maturation.
Using proteomics techniques to study injured optic nerves, researchers at Boston Children’s Hospital have identified previously unrecognized proteins and pathways involved in nerve regeneration. The new study showed that adding … Continue Reading Researchers see an unprecedented degree of nerve regeneration using proteomics.