During neurodevelopment, the brain fabricates an incredible number of neurons which then migrate to specific parts of the brain. The development of new neurons is active all the way through … Continue Reading Study identifies how adult brain circuits regulate new neuron production.
Wound repair is an important aspect of physiology, and disruption of this process can result in a number of defects involving wound healing, chronic ulceration and scarring. A scar on … Continue Reading Study pinpoints protein that helps to regulate wound healing.
Mammalian skeletal muscles can regenerate following injury and this response is mediated by a specific type of stem cell, the satellite cell. Significant evidence suggests that while stem cells represent … Continue Reading Previously unknown mechanism in skeletal muscle regeneration identified.
Acute kidney injury (AKI) is characterized by an abrupt decline in kidney function, leading to the accumulation of toxic waste products of cellular metabolism and derangement of electrolyte balance. Despite … Continue Reading Researchers identify gene which initiates the repair of acutely injured kidneys.
Intracardiac septal defects are the most common congenital defects in the young. The gold standard treatment is suture-based surgical closure, requiring cardiopulmonary bypass, which can increase the risk of pump-related … Continue Reading Catheter can fix holes in the heart without invasive surgery.
Dividing cells are prone to errors, and so they must be prepared to summon sophisticated emergency systems to deal with potential damage. One type of division-derailing mishap can occur when … Continue Reading Researchers identify previously unknown part of the ICL DNA repair pathway.
Chronic spinal cord injury (SCI) is a formidable hurdle that prevents a large number of injured axons from crossing the lesion, particularly the corticospinal tract (CST). Patients inflicted with SCI … Continue Reading Researchers identify precision medicine to regenerate corticospinal tract axons.
Researchers have identified the first oncogenes responsible for the brain tumour, choroid plexus carcinoma.
Researchers have identified three genes that play a pivotal role in the brain tumour, choroid plexus carcinoma (CPC), a discovery that lays the groundwork for more effective treatment of this … Continue Reading Researchers have identified the first oncogenes responsible for the brain tumour, choroid plexus carcinoma.
Human DNA accumulates damage over time, and older people’s bodies can’t repair it as well. Many scientists believe a build up of damage can cause cells to enter an irreversible … Continue Reading Study identifies molecular link between DNA damage and premature aging.
A protein that helps embryonic stem cells retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that … Continue Reading Researchers identify protein responsible for DNA repair at a stem cell level.
Case Western Reserve researchers have identified a two-pronged therapeutic approach that shows great potential for weakening and then defeating cancer cells. The team’s complex mix of genetic and biochemical experiments … Continue Reading Cancer treatment identified in gene repair pathway.
Mice and humans share a lot more than immediately meets the eye, and their commonalities include their telomeres, protective ends on chromosomes. But in recent years, the role of one … Continue Reading Study resolves decade-long argument over protein’s role at telomeres.