Containing a mini-ecology of its own, the human gut contains trillions of bacteria, known as the microbiota, a symbiotic entity crucial for digesting food and regulating the immune system. Gut … Continue Reading Gut microbiota that impairs normal skeletal growth identified.
In his famous experiment, Ivan Pavlov rang a bell each time he fed his dogs, which resulted in the animals drooling in anticipation every time they heard the bell, even … Continue Reading Study identifies the brain cells regulating the Pavlovian response.
Through millions of years of trained evolution, all living organisms adapt their behavior in response to infection, however, the mechanisms behind this are less understood. Now, a study led by … Continue Reading Neurons regulate reproduction in fruit flies during infection.
The inflammatory response is an integral part of the innate immune mechanism that is triggered in response to a real or perceived threat to tissue homeostasis, with a primary aim … Continue Reading New class of molecule identified in central role of inflammation and the immune system.
The WHO recommends complete withdrawal of the oral polio vaccine (OPV) by April 2016 globally and replacing with at least one dose of inactivated poliovirus vaccine (IPV). However, high-cost, limited … Continue Reading Researchers develop plant-based Polio booster vaccine.
Alzheimer’s disease is a devastating and progressive neurodegenerative disease affecting approximately 5.3 million people in the United States, including almost half of the population at 85 years and older. Microscopic hallmarks … Continue Reading New blood test detects early Alzheimer’s in large-scale study with unprecedented sensitivity.
Acute HIV-1 infection is the phase of HIV-1 disease immediately after infection that is characterized by an initial burst of viremia; although anti-HIV-1 antibodies are undetectable, HIV-1 RNA or p24 … Continue Reading Study captures HIV study early to successfully characterise the elusive acute infection period.
HIV, is a virus that attacks the body’s immune system. If left untreated, HIV can progress and develop into AIDS. HIV infection is enhanced by adhesive structures that form between … Continue Reading First-ever study captures HIV cell-to-cell transmission in a living animal.
A person’s genetic makeup plays a role in autoimmune diseases such as multiple sclerosis that develop when the body is attacked by its own immune system. However, little is known … Continue Reading Study maps gene variants to DNA regions that regulate immune cells.
T cells are the immune cells responsible for recognizing and destroying specific invaders, such as viruses, bacteria, or cancer. Their activity is highly tunable, with signals from other cells adjusting … Continue Reading Study identifies a new regulator of immune responses.
The intestines’ primary role is digestion, however, they must also achieve high performance around the clock defending against pathogens and environmental pollutants. This is because everything taken up with food … Continue Reading Study shows how an important intestinal immune response controller works.
A fundamental question in human immunodeficiency virus 1 (HIV-1) research is why the immune system is unable to contain the virus. Unlocking this key would provide a significant advance in … Continue Reading New study explains why HIV is not cleared by the immune system.
Allergies are characterized by inappropriate inflammatory responses to benign environmental antigens. Primary clinical approaches to allergic disease consist of symptom control or administration of soluble antigens to skew the immune response … Continue Reading Novel nanoparticle acts like Trojan horse to halt asthma in animal model.
Systemic lupus erythematosus (SLE) is a common autoimmune disorder in which the body’s immune system mistakenly attacks healthy tissues, it can affect the skin, joints, kidneys, brain, and other organs. … Continue Reading Study shows how mitochondria drives autoimmune response in lupus.
The earliest events that occur following mucosal HIV-1 exposure remain poorly understood, largely because the eclipse period of infection prior to the detectable disease is very difficult to study in … Continue Reading Earliest ever events following HIV infection mapped for the first time.
Psoriasis is a chronic autoimmune disorder that affects 2% of the world population. It is characterised by inflammation and scaling of the skin, accompanied by a greater risk of contracting … Continue Reading Researchers identify a link between psoriasis and bone loss.