The sugar epidemic in America has reached deadly proportions with the average person’s intake of this substance now averaging more than 100 pounds annually. Sugar addiction has been linked to … Continue Reading Researchers discover a new gut-to-brain sugar pathway.
To maintain homeostasis in the body, physiological imbalances produce motivational drives, one of which is thirst. This thirst produces a drive to seek and consume water, however, just how neural activity … Continue Reading Quench thirsting neurons in the brain identified.
Alcoholism is a chronic relapsing disorder associated with compulsive drinking, loss of control over intake, and emergence of a negative emotional state during abstinence from the drug. Special emphasis has … Continue Reading Researchers target neurons involved in compulsive drinking to reverse alcohol dependence in rats.
It is known that repeated cocaine-use results in the development of behavioural sensitization, accompanied by a decrease in excitatory synaptic strength in the nucleus accumbens (NAc). Furthermore, glial cells in … Continue Reading Microglia-based mechanism that reduces effect of cocaine on the brain identified.
Cocaine is a strong central nervous system stimulant that increases levels of the neurotransmitter dopamine in brain circuits regulating pleasure and movement. Normally, dopamine is released by neurons in these … Continue Reading Researchers begin to map brain regions and circuits changed by cocaine-use.
In the treatment of pain, a common course is to treat patients with opioid medications, these medications show limited effectiveness for neuropathic pain and come with safety and addiction issues. … Continue Reading Researchers map how antidepressants lessen neuropathic pain.
Scientists at The Scripps Research Institute (TSRI) have discovered that a brain protein has a key role in controlling binge drinking in animal models. They found that deleting the gene … Continue Reading Researchers identify brain protein responsible for controlling binge- drinking.
A chemical in the brain typically associated with cognition, movement and reward-motivation behaviour, among others, may also play a role in promoting chronic pain, according to new research from researchers … Continue Reading Researchers map dopamine based chronic-pain pathway in the spinal cord and brain.
Researchers successfully implant and control light-sensitive opioid receptors in mice via optogenetics.
Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp … Continue Reading Researchers successfully implant and control light-sensitive opioid receptors in mice via optogenetics.
Researchers at Aalto University and University of Turku have revealed how obesity is associated with altered opioid neurotransmission in the brain. New research reveals how obesity is associated with altered … Continue Reading Neuroimaging study maps brain neurotransmission system involved in obesity.
Researchers at the University of Copenhagen have gained new insight into the mechanism behind a protein dopamine transporter that could help in the development of future medical treatment against cocaine … Continue Reading Researchers one-step closer towards an antidote for cocaine addiction.
Within a few months after drug withdrawal, patients in recovery from dependence on prescription pain medications may show signs that the body’s natural reward systems are normalizing. The study from … Continue Reading Researchers map clinical neuroimaging markers for opioid withdrawal.