Astrocytic ‘uncoupling’ identified and reversed in temporal lobe epilepsy.

Epilepsy is a very prevalent neurological disorder. Approximately one-third of patients are resistant to currently available therapies. A team of researchers from the University of Bonn has discovered a new cause to explain the development of temporal lobe epilepsy,  at an early stage astrocytes are uncoupled from each other. This results in the extracellular accumulation of potassium ions and neurotransmitters, which cause hyperexcitability of the … Continue reading Astrocytic ‘uncoupling’ identified and reversed in temporal lobe epilepsy.