Memorizing and predicting aversive or unpleasant events is a critical function of neural circuits responsible for survival and emotional well-being. There is much interest in how the brain creates the … Continue Reading Brain pathways of aversion identified.
Major depressive disorder is a highly familial illness and the leading cause of disability worldwide for persons 15 to 44 years of age. It is associated with increased mortality resulting … Continue Reading Study shows that both genetics and environment impact depression.
Low levels of serotonin in the brain are known to play a role in depression and anxiety, the involvement of serotonin (5-HT) in regulating emotional behaviour is firmly established. In … Continue Reading Researchers uncover new serotonin neuronal mechanism in depression.
The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors, are a group of G protein-coupled receptors and ligand-gated ion channels found in the central and peripheral nervous systems. … Continue Reading Researchers identify previously unknown subtypes of 5HT neurons.
In the treatment of pain, a common course is to treat patients with opioid medications, these medications show limited effectiveness for neuropathic pain and come with safety and addiction issues. … Continue Reading Researchers map how antidepressants lessen neuropathic pain.
Prions are proteins in which the complex molecular three-dimensional folding process has simply gone astray. For reasons not yet understood, the misfolding nature of prions is associated to their ability … Continue Reading Study shows that the prion protein plays a role in depression.
Although serotonin is well known as a brain neurotransmitter, it is estimated that 90 percent of the body’s serotonin is made in the digestive tract. In fact, altered levels of … Continue Reading Researchers identify gut’s role in peripheral serotonin production and shaping the nervous system.
Depression affects an estimated 350 million people worldwide and poses a major public health challenge, according to the World Health Organization. Researchers have discovered an unconventional way that serotonin is … Continue Reading New source of serotonin in the brain found and the effects on SSRI’s identified.
Researchers from the University of Bern have discovered a mechanism that is responsible for the level of chronic pain in the brain. The results of this study point to new … Continue Reading Researchers begin to map chronic pain memory in the brain.
Neurobiologists at NYU Langone, University of Pennsylvania, University of Lyon and Linkoping University have found a surprising and paradoxical effect of abuse-related cues in rat pups, those cues also can lower depressive-like behaviour … Continue Reading Neuroimaging maps cues associated with infant abuse which help to reduce stress in the adult brain.
Why do some people develop post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA discovery may shed light on the answer. UCLA scientists … Continue Reading Study identifies two genes that boost risk for post-traumatic stress disorder.
Even with modern whole-genome sequencing techniques, it has proven difficult to identify genetic factors affecting risk for depression, according to an opensource literature review in the Harvard Review of Psychiatry. … Continue Reading Harvard-led literature review on genetics in depression, what’s known, what’s next.
Vitamin D deficiency is not just harmful to physical health, it also might impact mental health, according to a team of researchers from the University of Pittsburgh and the Queensland … Continue Reading Vitamin D deficiency, lack of sunlight and depression linked in international study.
Researchers at Karolinska Institutet have succeeded in explaining how stem cells in the brain change to allow one type of stem cell to produce different cell types at different stages. … Continue Reading First known molecular signalling control for neurogenesis identified.
With the aid of new methods, a research team at Karolinska Institutet have developed a detailed map of the networks of the brain that control the neurotransmitter serotonin. The study, … Continue Reading Discovery of new pathways controlling the serotonergic system.
Scientists studying depression in teens have discovered that subtle changes in a gene can predict how the brain reacts to stress, which can cause such health issues as depression, post-traumatic … Continue Reading Researchers find multiple new predictors of stress-related illnesses.