Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease affecting motor neurons. This fatal disease is characterized by progressive muscular atrophy and doesn’t have an effective treatment. Patients with … Continue Reading Study provides first definitive evidence and description of protein clump toxicity in ALS.
A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If not, the defective … Continue Reading Researchers identify the role mitochondria plays in familial ALS.
Using a technique that illuminates subtle changes in individual proteins, chemistry researchers at Cornell and Scripps Research Institute have uncovered new insight into the underlying causes of Amyotrophic Lateral Sclerosis (ALS). … Continue Reading Cornell scientists show that ALS is a protein aggregation disease.