The female uterus is essential for reproduction in all mammals, meaning any trauma or disease affecting this organ detrimentally could compromise a woman’s ability to conceive or carry a viable … Continue Reading A tissue-engineered uterus supports live births in rabbits.
In vitro testing is the controlled process of testing biological materials outside of the living organism in a synthetic environment set-up within laboratory equipment. Experimenting with tissues in culture can … Continue Reading Microfluid device kept live brain tissue functional for 25 days.
Approximately half the adult population in the United States is suffering from back or neck pain whose treatment and care costs result in an estimated 195 billion USD a year. … Continue Reading Spinal discs made of engineered living tissue implanted in large animal model.
In evolutionary biology, protocells are thought to be a stepping-stone to the origin of life, hypothesized as the first cells to transfer genetic information via RNA before the onset of … Continue Reading Researchers develop synthetic prototissue capable of synchronized beating.
Lung disease causes more than 200,000 deaths annually in the United States. Although the lung is generally considered slow to respond to disease and injury, it does undergo regenerative processes, … Continue Reading Researchers develop tissue-engineered model of human lung and trachea.
Obesity is a global health problem that poses a major risk factor for life-threatening diseases such as cardiovascular disease, cancer, and neurodegeneration. Recent studies have identified specific loci associated with … Continue Reading Study maps a molecular link between insulin-sensitivity and obesity.
Body mass index (BMI) is an important risk factor for breast cancer development and invasiveness. After menopause, women have an increased risk of developing breast cancer with increased BMI, while … Continue Reading New MRI technique links saturated fats to breast cancer in postmenopausal women.
Worldwide obesity has more than doubled since 1980. In 2014, there were over 600 million people classified as obese, making up 13% of the global population. Researchers have long known … Continue Reading Researchers stimulate brown-fat in animals to improve weight-management and glucose control.
Pancreatic cancer is a devastating disease, with a death rate close to the incidence rate. Because more than 90% of pancreatic cancer cases are diagnosed at the metastatic stage, when … Continue Reading Early indicators of pancreatic cancer identified in precision medicine study.
Brown adipose tissue, brown fat, is a key tissue that controls the energy balance of whole body. Excessive energy is dissipated in the form of heat by brown adipocytes specialized … Continue Reading Study identifies pathway in brown fat responsible for better metabolism.
It is known that cardiac natriuretic peptides (NPs) are hormones produced by the heart to influence blood pressure. When the heart senses elevated pressure, it releases NPs, which go to the … Continue Reading Human study identifies link between heart hormones, obesity, and diabetes.
It is known that diabetes is a disease that commonly inflicts the pancreas, the organ responsible for insulin production. More specifically, it inflicts the cells that produce insulin, which are … Continue Reading Researchers identify a previously unknown developmental cause of diabetes.
Current estimates place obesity incidence at more than 600 million individuals worldwide. As a prime risk factor for heart disease, stroke, cancer, type 2 diabetes, and neurodegeneration, obesity poses a … Continue Reading Researchers identify an epigenetic switch for obesity.
White adipose tissue, or fat tissue, serves as a storage depot for energy-rich triglycerides. In times of need this lipid storage can be released as part of an adaptive response … Continue Reading Researchers identify previously unknown neural mechanism responsible for fat breakdown.
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health, leading to reduced life expectancy and … Continue Reading Researchers link obesity to a faulty immune system in animal model.
Triglycerides, like cholesterol, are lipids. They come from fats carried by food or produced by the human body. Depending on the cause, the accumulation of triglycerides in blood is associated … Continue Reading Researchers use precision medicine to reduce the amount of fat in patient’s blood.