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Researchers led by Columbia Engineering demonstrate severely injured donor lungs declined for transplant can be recovered outside the body by a system utilizing cross-circulation of whole blood between the donated lung and an animal host. The team states human lungs unsuitable for transplant can be recovered using their new transgenic cross-circulation system, with the hope it may provide a much larger number of organ transplants to critically ill patients.

Severely damaged human lungs successfully recovered using transgenic system.

An extremely common condition rising at an alarming rate due to environmental and lifestyle causal elements, respiratory disease is the third leading cause of death worldwide. Despite the copious amounts … Continue Reading Severely damaged human lungs successfully recovered using transgenic system.

Researchers successfully implant and innervate bioengineered teeth derived from postnatal cells.

Tooth loss is a major public health issue affecting more than 158 million people worldwide. The current standard of care is to replace missing teeth with synthetic dental implants, and/or … Continue Reading Researchers successfully implant and innervate bioengineered teeth derived from postnatal cells.

Tiny drug-delivering capsules could sustain transplanted insulin-producing cells.

Researchers have long explored ways to transplant pancreatic islets to treat type I diabetes in the long term to eliminate the need for continuous glucose monitoring and insulin injections. However, … Continue Reading Tiny drug-delivering capsules could sustain transplanted insulin-producing cells.

Unprecedented precision study identifies the four genes responsible for blood stem cell development.

Every day, over 100 billion new mature blood cells are generated in an adult human. This major production places high demands on the blood stem cells which must be capable … Continue Reading Unprecedented precision study identifies the four genes responsible for blood stem cell development.

Human stem cell-derived kidneys connect to blood vessels when transplanted into mice.

In the field of iPS cell-based regenerative medicine, advanced research with clinical applications for many organs and tissues, such as the retina, has steadily progressed. However, growing a kidney from … Continue Reading Human stem cell-derived kidneys connect to blood vessels when transplanted into mice.

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