For people dealing with the life-changing and often devastating aftermath of disfiguring injuries or the loss of limbs, minimal reconstruction using the patients’ own tissues may not be a sufficient … Continue Reading Synthetic cell biomimics cancer to avoid transplant rejection.
In the past chimeras, an unnatural amalgamation of two different species was the stuff of futuristic sci-fiction comics, today this promising genetic engineering technique is less scary as it becomes … Continue Reading First pig-monkey chimera engineered and born.
Nearly 12 million adults in the United States have been diagnosed with chronic obstructive pulmonary disease, with roughly 180,000 patients dying annually with end-stage refractory lung diseases. The only option … Continue Reading Donor stem cells used to grow fully functioning lungs in live mice.
According to the CDC, Bacterial Vaginosis (BV) is the most common vaginal infection in women aged between 15 and 44, affecting an estimated 21.2 million women nationwide. BV is associated … Continue Reading Researchers developing vaginal microbiota transplant to treat bacterial vaginosis.
Organ donation is where a live or deceased person consents to having one or more of their organs removed and transplanted to another person. Unfortunately, there’s currently an organ shortage … Continue Reading Synthetic biology used to develop cornea capable of self-assembly.
Tooth loss is a major public health issue affecting more than 158 million people worldwide. The current standard of care is to replace missing teeth with synthetic dental implants, and/or … Continue Reading Researchers successfully implant and innervate bioengineered teeth derived from postnatal cells.
Researchers have long explored ways to transplant pancreatic islets to treat type I diabetes in the long term to eliminate the need for continuous glucose monitoring and insulin injections. However, … Continue Reading Tiny drug-delivering capsules could sustain transplanted insulin-producing cells.
Unprecedented precision study identifies the four genes responsible for blood stem cell development.
Every day, over 100 billion new mature blood cells are generated in an adult human. This major production places high demands on the blood stem cells which must be capable … Continue Reading Unprecedented precision study identifies the four genes responsible for blood stem cell development.
The liver plays a critical role in how the body metabolizes drugs and produces key proteins. This is why liver models are increasingly being developed in the lab as platforms … Continue Reading Researchers successfully 3D-print biomimetic liver tissue for drug screening.
Kidney failure is a growing problem in the United States, every year, approximately 10,000 kidneys become available for transplant into patients with end-stage kidney disease. However, the waiting lists for … Continue Reading Mammalian kidney identified as a ‘blood-generating’ organ for the first time.
In the field of iPS cell-based regenerative medicine, advanced research with clinical applications for many organs and tissues, such as the retina, has steadily progressed. However, growing a kidney from … Continue Reading Human stem cell-derived kidneys connect to blood vessels when transplanted into mice.
The skin is the largest organ in the human body and is made up of three layers, the epidermis, dermis and the fat layer. The epidermis is the outer layer … Continue Reading Artificially intelligent synthetic skin interacts with brain cells.
Sickle cell disease is inherited. It primarily affects people of African descent, including about one in every 500 African Americans born in the U.S. The defect causes the oxygen-carrying red … Continue Reading Researchers validate non-chemotherapy based cure for sickle cell in adults.
Of all the body’s major organs the liver has the highest capacity to regenerate and that’s why many liver diseases, including cirrhosis and hepatitis, can often be cured by transplanting … Continue Reading Researchers discover cells that regenerate the liver without forming tumours.
Surgeons at The Children’s Hospital of Philadelphia (CHOP) joined with colleagues from Penn Medicine recently to complete the world’s first bilateral hand transplant on a child. Earlier this month, the … Continue Reading Surgeons perform the world’s first successful bilateral hand transplant on a child.
A petite 44-year-old woman has become the first patient in the world to be bridged to a successful heart transplant, that is, to go from needing a transplant to receiving … Continue Reading First patient in the world bridged to a successful heart transplant via a Total Artificial Heart.