Infectious diseases continue to affect and kill a multitude of people worldwide, with vaccination seen as the most powerful weapon against this threat. Vaccines are prepared from weakened forms of … Continue Reading Synthetic vaccine can be stored at warmer temperatures.
The Zika virus is a mosquito-borne disease designated a global public health concern, with more than two billion people at risk. For most people Zika manifests as a mild infection, … Continue Reading Synthetic antibody protects mice and monkeys from Zika.
When a person is exposed to an infection, they are often protected from getting the same infection again by immune memory, the part of the immune system capable of remembering … Continue Reading New part of the immune system identified, expected to evolve vaccination.
The WHO recommends complete withdrawal of the oral polio vaccine (OPV) by April 2016 globally and replacing with at least one dose of inactivated poliovirus vaccine (IPV). However, high-cost, limited … Continue Reading Researchers develop plant-based Polio booster vaccine.
The human immunodeficiency virus (HIV) is a lentivirus which causes HIV infection and over time AIDS. Developing effective prevention measures for HIV is hindered by incomplete knowledge of the phenotype … Continue Reading New technology lights up location of first cells to be infected in female HIV transmission.
Nanovaccine successfully protects against primary and secondary female genital herpes infections in animals.
Herpes simplex virus-2, which causes serious eye infections in newborns and immunocompromised patients as well as genital herpes, is one of the most common human viruses. According to the Centers … Continue Reading Nanovaccine successfully protects against primary and secondary female genital herpes infections in animals.
Envelope glycoprotein GP120 is a glycoprotein exposed on the surface of the HIV envelope (ENV). The envelope glycoprotein trimer is essential for HIV entry into cells as it plays a … Continue Reading New breakthrough imaging shows HIV structure in unprecedented detail.
In recent years, Ebola outbreaks have increased in frequency, duration, and geographical spread, underscoring the need for pre- and post-exposure treatments. Antibodies targeting the Ebola virus surface glycoprotein, the viral structure … Continue Reading Previously unknown ebola-fighting antibodies identified in outbreak survivor’s blood.
When pathogens infect the cells of the body, the infection sets off a chain reaction involving the immune system that changes the expression of hundreds of genes. Gene expression is … Continue Reading Multiple signatures left on the immune system by viral infections identified for the first time.
MERS is caused by an emerging human coronavirus, which is distinct from the SARS coronavirus. Since its identification in 2012, MERS has been linked to over 1,300 infections and close … Continue Reading New synthetic-DNA vaccine protects against MERS in simian model.
A collaborative team from The University of Texas and the National Institutes of Health have developed an inhalable vaccine that successfully protects primates against Ebola in simian trials. The team … Continue Reading First ever inhalable ebola vaccine is successful in simian trials.
New technology developed by Howard Hughes Medical Institute (HHMI) and Brigham and Women’s Hospital researchers makes it possible to test for current and past infections with any known human virus by … Continue Reading New bacteriophage-based assay gives a person’s whole viral infection history in a drop of blood.
New ‘can-opener’ molecule forces HIV virus open to expose vulnerable regions for antibodies to kill.
The human immunodeficiency virus (HIV) is often likened to a hermetically sealed tin can no one has yet been able to break open. Now, researchers at the University of Montreal … Continue Reading New ‘can-opener’ molecule forces HIV virus open to expose vulnerable regions for antibodies to kill.
An international consortium from the TU Dresden and the Helmholtz Zentrum München, together with researchers from Vienna, Bristol and Denver (USA) have successfully completed the first step in development of … Continue Reading Researchers complete the first human trials for insulin vaccine to prevent T1 diabetes.
In a study that included approximately 95,000 children with older siblings it has been shown that receipt of the measles-mumps-rubella (MMR) vaccine was not associated with an increased risk of … Continue Reading Large-scale study finds no link between MMR vaccine and autism, even among children at higher risk.
Researchers from the Garvan Institute of Medical Research have discovered a new population of ‘memory’ immune cells, throwing light on what the body does when it sees a microbe for the … Continue Reading Researchers discover a new type of ‘memory’ immune cell.