Vital to our bodies, preproglucagon otherwise known as GCG peptides act in both the periphery and the CNS to change food intake, glucose homeostasis, and metabolic rate. Although the actions … Continue Reading Neurons successfully regulate appetite and glucose levels in mice.
An intricate sensory network intertwined across our bodies, the nervous system requires a specialized network of blood vessels for its development and survival. However, it is still unclear as to … Continue Reading Study shows that neurons modulate the growth of blood vessels.
Welcome to The Top Ten Healthinnovations of 2016, the third-year in our successful series, where the most exciting discoveries and breakthroughs are decided by you, the global medical community. This … Continue Reading The Top Ten Healthinnovations of 2016.
A germline mutation is any detectable and heritable variation in the lineage of germ cells, any biological cell that gives rise to the gametes of an organism in sexual reproduction. … Continue Reading Study provides most detailed analysis yet of germline mutations involved in childhood cancers.
Inflammatory bowel disease (IBD) is a painful, chronic inflammation of the gastrointestinal tract, affecting roughly two million children and adults in the U.S. Inflammatory bowel disease (IBD) beginning in childhood tends … Continue Reading Study identifies gene variants in inflammatory bowel disease under Age 5.
Autism spectrum disorder (ASD) represents a diverse group of neurodevelopmental conditions. The clinical presentation and outcome vary substantially. The use of genome-wide tests to provide molecular diagnosis for individuals with … Continue Reading Study identifies children with Autism who benefit from genetic testing.
Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent … Continue Reading Researchers identify new gene responsible for liver disease.
Researchers at the Spanish National Cancer Research Centre (CNIO) have described the presence of mutations in the MDH2 gene, in a family with very rare neuroendocrine tumours associated with a … Continue Reading Researchers identify point of epigenetic mutation of hereditary neuroendocrine tumours.
Leprosy is a chronic infection of the skin, peripheral nerves, eyes and mucosa of the upper respiratory tract, affecting over a quarter million people worldwide. Its symptoms can be gruesome … Continue Reading The genomes and origins of the leprosy bacterias compared for the first time.
Even with modern whole-genome sequencing techniques, it has proven difficult to identify genetic factors affecting risk for depression, according to an opensource literature review in the Harvard Review of Psychiatry. … Continue Reading Harvard-led literature review on genetics in depression, what’s known, what’s next.
DNA sequences were once thought to be identical from cell to cell, but it’s increasingly understood that mutations can arise during brain development that affect only certain groups of brain … Continue Reading New single-cell sequencing technique can track subtle neurogenetic mutations spatially.
UT Southwestern Medical Center researchers have demonstrated that whole-genome sequencing can be used to identify patients’ risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, diagnosis, … Continue Reading Researchers confirm whole-genome sequencing can identify cancer-related mutations and risk.
Premature ovarian failure, also known as primary ovarian insufficiency (POI), affects 1% of all women worldwide. In most cases, the exact cause of the condition, which is often associated with … Continue Reading Genetic mutation identified as cause of human ovarian failure.