The mammalian Y chromosome encodes a specialized set of genes that are essential for male viability and fertility. In particular, the sex-determining region Y (SRY) protein is necessary to initiate … Continue Reading Male mice without any Y chromosome produce offspring with assisted reproduction.
In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and … Continue Reading Researchers identify a new gene responsible for male infertility.
Fragile X syndrome, an inherited cause of autism and intellectual disability, can have consequences even for carriers of the disorder who don’t have full-blown symptoms. Some carriers may experience social … Continue Reading New previously unseen cellular mechanism identified in Fragile X syndrome.
The micro RNA miR-22 has long been known for its ability to suppress cancer. However, questions remain about how it achieves this feat. For example, which molecules are regulating miR-22, … Continue Reading Researchers being to map the epigenetic pathway of miR-22 cancer suppression.
Scientists from the Washington University and Emory University have gained new insight into fragile X syndrome, the most common cause of inherited intellectual disability, by studying the case of a … Continue Reading New genetic clues found in fragile X syndrome.
Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability (ID), as well as the most frequent monogenic cause of autism spectrum disorders (ASD). FXS is caused … Continue Reading New neurodevelopmental insights that link Fragile X syndrome and autism spectrum disorders.