In oncology, the Warburg effect is the observation that that the driver of tumourigenesis is an insufficient cellular respiration caused by insult to mitochondria. It postulates that most cancer cells, … Continue Reading Study uncovers vital Warburg effect pathway in brain tumour formation and metabolism.
Telomere dysfunction has been proposed as a key event that causes cancer progression. According to this model, progressive telomere shortening results in telomere dysfunction and end-to-end chromosomal fusions. The resulting … Continue Reading Researchers identify telomere-based mechanism which turns mutant cells into aggressive cancers.