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Researchers led by VIB-KU Leuven discover a population of specialized brain-resident white blood cells in the mouse and human brain, and show that the presence of these lymphocytic cells is essential for normal brain development in mice. The team states these results contribute towards the increasing recognition of the role of circulating immune cells in the brain and their involvement in a range of neurological diseases.

New role for white blood cells in the developing brain.

Our onboard computer, the brain, is a sterile environment separated from the immune system by the blood-brain barrier (BBB), which is why it has its own resident immune cells, known … Continue Reading New role for white blood cells in the developing brain.

Immune cells identified as the culprit linking hypertension and dementia.

Hypertension is a leading risk factor for dementia, however, the mechanisms underlying its damaging effects on the brain are poorly understood.  Now, a study from researchers at Weill Cornell Medicine … Continue Reading Immune cells identified as the culprit linking hypertension and dementia.

Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.

Alzheimer’s disease is characterized by the degeneration of neurons in the hippocampus and cortex, and the appearance of neuritic plaques and neurofibrillary tangles.  Although the precise cause of Alzheimer’s disease remains … Continue Reading Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.

Researchers derive first ever molecular model of critical blood-brain barrier transporter.

Presently, there are limitations to drug delivery to the brain as it is tightly protected by the blood-brain barrier. The blood-brain barrier is a protective barrier which separates the circulating … Continue Reading Researchers derive first ever molecular model of critical blood-brain barrier transporter.

New technique bypasses the blood-brain barrier to deliver neuroprotection.

The blood-brain barrier represents a fundamental limitation in treating neurological disease because it prevents all neuropeptides from reaching the central nervous system (CNS). Currently, there is no efficient method to … Continue Reading New technique bypasses the blood-brain barrier to deliver neuroprotection.

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