This is the sixth year running in the popular Top 10 Healthinnovations series, a list of the most viewed articles for the year on the Healthinnovations site. This is where … Continue Reading The Top 10 Healthinnovations of 2019.
Depression is the leading cause of disability worldwide, affecting more than 300 million people globally, characterized by persistent sadness and a loss of interest in activities, accompanied by an inability … Continue Reading Gender-distinct circuit for depression identified in mice.
Chronic pain is defined as any persistent pain which lasts more than 3 months, with research indicting over 85% of patients suffering from chronic pain are affected by severe depression, … Continue Reading Molecular link between chronic pain and depression identified.
Causing contrasting episodes of mania and depression bipolar disorder (BD) can be an exhausting illness. BD is a chronic and recurrent mental disorder with a worldwide prevalence of around 0.8%, … Continue Reading Gut microbiota significantly different in patients with bipolar disorder.
Memorizing and predicting aversive or unpleasant events is a critical function of neural circuits responsible for survival and emotional well-being. There is much interest in how the brain creates the … Continue Reading Brain pathways of aversion identified.
The link between the gut microbiota, also known as the second brain, and mental health has long been studied. The idea of substances produced by the symbiotic microorganisms in the … Continue Reading Gut microbiome linked to mental health.
Self-harm is when somebody intentionally damages or injures their body as a way of coping with very difficult feelings, painful memories or overwhelming situations. Self-inflicted injury in adolescence is a … Continue Reading Neuroimaging maps brain changes in self-harming teenage girls.
Mental illness, particularly bipolar disorder and depression, can be difficult to diagnose as many conditions have similar symptoms. These two illnesses are virtually identical except individuals with bipolar disorder also … Continue Reading Neuroimaging distinguishes between bipolar disorder and depression in human study.
It is known that a 24-hour circadian rhythm controls nearly all brain and body processes, such as the sleep/wake cycle, metabolism, alertness and cognition. These daily activity patterns are regulated … Continue Reading Researchers map the circadian neurogenetics involved in brain aging.
Major depressive disorder is a highly familial illness and the leading cause of disability worldwide for persons 15 to 44 years of age. It is associated with increased mortality resulting … Continue Reading Study shows that both genetics and environment impact depression.
Many patients with bipolar disorder, a debilitating mental condition that can take a person from the sluggishness of severe depression to super-human energy levels, are often misdiagnosed as having major … Continue Reading Medicalising, differentiating between major depressive and bipolar disorder.
Low levels of serotonin in the brain are known to play a role in depression and anxiety, the involvement of serotonin (5-HT) in regulating emotional behaviour is firmly established. In … Continue Reading Researchers uncover new serotonin neuronal mechanism in depression.
The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors, are a group of G protein-coupled receptors and ligand-gated ion channels found in the central and peripheral nervous systems. … Continue Reading Researchers identify previously unknown subtypes of 5HT neurons.
Antidepressants are recommended as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy. Experts recommend against their … Continue Reading Study maps structural brain changes caused by antidepressants.
Everyone occasionally feels blue or sad. However, these feelings are usually short-lived and pass within a couple of days. When a person has depression, it interferes with daily life. Depression … Continue Reading Study identifies new diagnostic brain protein in depression.
In the treatment of pain, a common course is to treat patients with opioid medications, these medications show limited effectiveness for neuropathic pain and come with safety and addiction issues. … Continue Reading Researchers map how antidepressants lessen neuropathic pain.