An ever-growing epidemic, obesity is a chronic medical condition where excess body fat has accumulated to the point it may cause a multitude of health disorders. Several studies have also … Continue Reading Visceral fat delivers a signal to the brain that impairs cognition.
Although bones are hard ossified organs, they have a dense network of blood vessels inside them where bone marrow is located. as well as on their outer surface covered by … Continue Reading Discovery of previously unknown blood vessel system in bones.
Approximately half the adult population in the United States is suffering from back or neck pain whose treatment and care costs result in an estimated 195 billion USD a year. … Continue Reading Spinal discs made of engineered living tissue implanted in large animal model.
Sepsis is the overreaction of the body’s immune system to infection capable of causing tissue damage, organ failure, and death. Sepsis-causing bacteria secrete toxic molecules known as endotoxins which trigger immune … Continue Reading Engineered macrophage nanosponges could keep sepsis in check.
Stress is the feeling of being under acute mental or emotional pressure, where a person may feel unable to cope, leading to a wide variety of health problems. When stress … Continue Reading Neuroimaging connects stress-associated brain activity to cardiovascular disease in humans.
Crohn’s disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient’s quality of life. Although people with the disease are typically treated with powerful … Continue Reading Researchers identify 2 distinct genetic subtypes in Crohn’s disease patients.
A significant milestone in the evolution of the mammalian brain is the emergence of the corpus callosum, which is exclusively present in placental mammals. This commissure forms the largest axon … Continue Reading Neuroimaging shows that astrocytes are responsible for joining the 2 halves of the brain together.
It is known that patients with Crohn’s disease have uncontrolled inflammation in their gut, which can lead to intestinal fibrosis and narrowing that can slow or block the movement of … Continue Reading Study identifies immune cells critical for the development of fibrosis in Crohn’s disease.
The inflammatory response is an integral part of the innate immune mechanism that is triggered in response to a real or perceived threat to tissue homeostasis, with a primary aim … Continue Reading New class of molecule identified in central role of inflammation and the immune system.
Generally, researchers divide the human immune system into two parts. One part, called the innate immune system, allows for immediate and direct recognition of invading bacteria. It prompts immune cells … Continue Reading Study identifies previously unknown mechanism of the immune system.
There is a clinical need for new, more effective treatments for chronic and debilitating inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. Now, a study from researchers at … Continue Reading Plant-based nanoparticles successfully treat inflammatory bowel disease in animal model.
Autism spectrum disorder (ASD) is a neurodevelopmental condition that manifests in early childhood and is characterized by impairments in social communication and presence of stereotyped behaviours and restricted interests, with … Continue Reading Mothers with diabetes more likely to have autism-linked anti-fetal brain autoantibodies.
The intestines’ primary role is digestion, however, they must also achieve high performance around the clock defending against pathogens and environmental pollutants. This is because everything taken up with food … Continue Reading Study shows how an important intestinal immune response controller works.
Genetic susceptibility is thought to play a role in common diseases including those affecting the colon such as inflammatory bowel diseases (IBD) and colorectal cancer. As is the case for … Continue Reading Study shows how gut microbiota interact with genes to promote Crohn’s disease.
Nanovaccine successfully protects against primary and secondary female genital herpes infections in animals.
Herpes simplex virus-2, which causes serious eye infections in newborns and immunocompromised patients as well as genital herpes, is one of the most common human viruses. According to the Centers … Continue Reading Nanovaccine successfully protects against primary and secondary female genital herpes infections in animals.
Allergies are characterized by inappropriate inflammatory responses to benign environmental antigens. Primary clinical approaches to allergic disease consist of symptom control or administration of soluble antigens to skew the immune response … Continue Reading Novel nanoparticle acts like Trojan horse to halt asthma in animal model.