An out-of-control pandemic still growing after many decades, chronic pain is the most common reason for physician consultation in most developed countries around the world, with almost one in five … Continue Reading Previously unknown sensory organ identified.
Organ donation is where a live or deceased person consents to having one or more of their organs removed and transplanted to another person. Unfortunately, there’s currently an organ shortage … Continue Reading Synthetic biology used to develop cornea capable of self-assembly.
In humans, the surgical removal of an ovary or ovaries is most often performed due to diseases such as ovarian cysts or cancer, or in conjunction with hysterectomy. In the … Continue Reading 3D-printed ovary bioprosthesis restores fertility in mice.
The liver plays a critical role in how the body metabolizes drugs and produces key proteins. This is why liver models are increasingly being developed in the lab as platforms … Continue Reading Researchers successfully 3D-print biomimetic liver tissue for drug screening.
Kidney failure is a growing problem in the United States, every year, approximately 10,000 kidneys become available for transplant into patients with end-stage kidney disease. However, the waiting lists for … Continue Reading Mammalian kidney identified as a ‘blood-generating’ organ for the first time.
In the field of iPS cell-based regenerative medicine, advanced research with clinical applications for many organs and tissues, such as the retina, has steadily progressed. However, growing a kidney from … Continue Reading Human stem cell-derived kidneys connect to blood vessels when transplanted into mice.
The skin is the largest organ in the human body and is made up of three layers, the epidermis, dermis and the fat layer. The epidermis is the outer layer … Continue Reading Artificially intelligent synthetic skin interacts with brain cells.
It’s been known that in the presence of obesity, the endoplasmic reticulum (ER) dysfunction is unable to perform one of its key functions: initiating a cascade of intracellular events called … Continue Reading New obesity-related mechanism identified in the development of Type 2 diabetes.
University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that … Continue Reading Reseachers identify and map progenitor cells for blood and immune cell production.
National Institutes of Health (NIH) researchers and their colleagues have developed a ‘placenta-on-a-chip’ to study the inner workings of the human placenta and its role in pregnancy. The device was … Continue Reading Researchers successfully develop placenta-on-a-chip which mirrors what occurs in the human body.
A team of Massachusetts General Hospital (MGH) investigators have made the first steps towards development of bioartificial replacement limbs suitable for transplantation. In their report the researchers describe using an … Continue Reading Researchers successfully bioengineer whole forelimb, transplant and reanimate it in animal model.
Researchers have solved century-old mystery of why lone kidneys grow larger when the one other is lost.
Researchers from Georgia Regents University, Vanderbilt University, Texas A&M University, and Northwestern University have found an explanation for the century-old observation that if a person ends up with just one kidney, … Continue Reading Researchers have solved century-old mystery of why lone kidneys grow larger when the one other is lost.
A multidisciplinary team of Vall d’Hebron University Hospital, led by Dr. Joan-Pere Barret, head of Plastic Surgery and Burns, have performed the world’s most complex successful face transplant. The team … Continue Reading Spanish hospital performs world’s most complex face transplant to-date.
Columbia University Medical Center (CUMC) researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or … Continue Reading Kidney transplant tolerance mechanism identified.
In a ground-breaking operation, a team of pioneering surgeons from Stellenbosch University (SU) and Tygerberg Hospital performed the first successful penile transplant in the world. The marathon nine-hour operation was … Continue Reading Surgeons perform the first successful penile transplant in the world.
Once-a-week nanoparticle injection successfully prevents corneal transplant rejection in animal study.
There are about 48,000 corneal transplants done each year in the U.S., compared to approximately 16,000 kidney transplants and 2,100 heart transplants. Out of the 48,000 corneal transplants done, 10 … Continue Reading Once-a-week nanoparticle injection successfully prevents corneal transplant rejection in animal study.