Depression is the leading cause of disability worldwide, affecting more than 300 million people globally, characterized by persistent sadness and a loss of interest in activities, accompanied by an inability … Continue Reading Gender-distinct circuit for depression identified in mice.
Causing contrasting episodes of mania and depression bipolar disorder (BD) can be an exhausting illness. BD is a chronic and recurrent mental disorder with a worldwide prevalence of around 0.8%, … Continue Reading Gut microbiota significantly different in patients with bipolar disorder.
Memorizing and predicting aversive or unpleasant events is a critical function of neural circuits responsible for survival and emotional well-being. There is much interest in how the brain creates the … Continue Reading Brain pathways of aversion identified.
Major depressive disorder is a highly familial illness and the leading cause of disability worldwide for persons 15 to 44 years of age. It is associated with increased mortality resulting … Continue Reading Study shows that both genetics and environment impact depression.
Large-scale study provides definitive proof that antidepressants during pregnancy increases autism risk.
Antidepressants are the first line of treatment for depression and anxiety for pregnant women, and they are able to cross the placenta. Not many studies have evaluated the effects of … Continue Reading Large-scale study provides definitive proof that antidepressants during pregnancy increases autism risk.
Many patients with bipolar disorder, a debilitating mental condition that can take a person from the sluggishness of severe depression to super-human energy levels, are often misdiagnosed as having major … Continue Reading Medicalising, differentiating between major depressive and bipolar disorder.
Low levels of serotonin in the brain are known to play a role in depression and anxiety, the involvement of serotonin (5-HT) in regulating emotional behaviour is firmly established. In … Continue Reading Researchers uncover new serotonin neuronal mechanism in depression.
The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors, are a group of G protein-coupled receptors and ligand-gated ion channels found in the central and peripheral nervous systems. … Continue Reading Researchers identify previously unknown subtypes of 5HT neurons.
Antidepressants are recommended as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy. Experts recommend against their … Continue Reading Study maps structural brain changes caused by antidepressants.
Everyone occasionally feels blue or sad. However, these feelings are usually short-lived and pass within a couple of days. When a person has depression, it interferes with daily life. Depression … Continue Reading Study identifies new diagnostic brain protein in depression.
In the treatment of pain, a common course is to treat patients with opioid medications, these medications show limited effectiveness for neuropathic pain and come with safety and addiction issues. … Continue Reading Researchers map how antidepressants lessen neuropathic pain.
Prions are proteins in which the complex molecular three-dimensional folding process has simply gone astray. For reasons not yet understood, the misfolding nature of prions is associated to their ability … Continue Reading Study shows that the prion protein plays a role in depression.
A new MRI study from the University of Pittsburgh has found distinct injury patterns in the brains of people with concussion-related depression and anxiety. The team state that the data … Continue Reading Neuroimaging begins to map post-concussion depression and anxiety in human study.
Brain inflammation caused by chronic nerve pain alters activity in regions that regulate mood and motivation, suggesting for the first time that a direct biophysical link exists between long-term pain … Continue Reading Researchers link microglia activation triggered by chronic pain to anxiety and depression.
A new study from researchers at the Douglas Institute and McGill University, suggests that the integration of new neurons in the adult brain is a phenomenon more generally compromised in … Continue Reading Human olfactory bulb neurogenesis study sheds light on depression.
Scientists use brain stimulation to boost creativity in human trials, set stage to treat depression.
A UNC School of Medicine study has provided the first direct evidence that a low dose of electric current can enhance a specific brain pattern to boost creativity by an … Continue Reading Scientists use brain stimulation to boost creativity in human trials, set stage to treat depression.