Cell ablation is an important tool for selectively destroying one or multiple cells in a given organism to remove a disease such as cancer or to produce the desired response through the removal of specific genomic loci.  A common form of ablation uses the diphtheria toxin, however, diphtheria crosses the blood-brain barrier which limits its utility for ablating cells in the peripheral nervous system (PNS).  … Continue reading Researchers successfully eliminate neurons outside the brain to trigger obesity.