Category Archives: chondrosarcoma

Researchers identify point of epigenetic methylation which drives cartilage tumour formation.


Duke researchers have identified that mutations in the isocitrate dehydrogenase (IDH) gene contribute to the formation of benign tumours in cartilage that can be a precursor to malignancies.  These benign tumours, known as enchondromas, are associated with severe pain, fractures, and skeletal deformities. They also have the potential to evolve into a cancerous form known as chondrosarcomas. Over 40% of

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