Cardiovascular diseases are the leading causes of death worldwide and represent a substantial economic burden on public health care systems. Now, a study from researchers at Uppsala University shows that … Continue Reading Large-scale study shows that memory, epigenetics of a heart attack are stored in person’s genes.
The children of traumatized people have long been known to be at increased risk for post-traumatic stress disorder (PTSD). However, there are very few opportunities to examine biologic alterations in … Continue Reading Trauma’s inherited epigenetic fingerprint observed in children of Holocaust survivors.
Obesity has become a major health threat, affecting more than half a billion people worldwide in 2014. In particular, obesity increases the risk for insulin resistance, hypertension, coronary heart disease … Continue Reading Epigenetic modification which raises obesity risk and predicts fatty liver identified.
Diffuse gliomas represent 80% of all malignant brain tumours. Adult diffuse gliomas are classified and graded according to histological criteria. However, although histopathology classification is well established it suffers from unstandardized, … Continue Reading Large-scale study identifies new epigenetic subtypes of brain cancer.
Type 2 diabetes is a chronic illness characterised by the presence of elevated blood glucose levels. It accounts for between 80 and 90% of diabetes cases and is one of … Continue Reading Large-scale study identifies an epigenetic marker for Type 2 diabetes.
Herpes simplex virus (HSV) is found in the brain cells of approximately 90% of the world’s population and leads to cold sores, recurrent eye infections, genital lesions, and in rare … Continue Reading Study shows how the herpes simplex virus reactivates in neurons.
DNA methylation is essential for the proper control of gene expression and cell identity, what enables cells with the same genetic material to become, for example, a nerve cell, a … Continue Reading Single-cell imaging developed which can record DNA methylation in real time.
Methylation is a process where a methyl group is added into critical points along human DNA. In cancer, many regions of the DNA are not methylated, leading to untimely gene … Continue Reading Researchers identify an epigenetic mechanism for colon cancer proliferation.
After it is transcribed from DNA, RNA can go on to many fates. While the most familiar path may lead directly to the production of protein, RNA molecules themselves can … Continue Reading Researchers unlock another piece of the RNA sequencing puzzle.
Cancer’s ability to grow unchecked is often attributed to cancer stem cells, a small fraction of cancer cells that have the capacity to grow and multiply indefinitely. How cancer stem … Continue Reading Researchers begin to map the epigenetic tags of glioblastoma.
Researchers at the University of Illinois have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells, the specialized cells that form blood vessels. Understanding the … Continue Reading Researchers begin to map the epigenetics that turn stem cells into blood vessel cells.
The results of a study presented today at the European League Against Rheumatism Annual Congress revealed that DNA methylation, a mechanism that regulates gene expression, could influence the progression of … Continue Reading First ever study maps the epigenetics of AS development caused by environmental factors.
Researchers at the University of Toronto have uncovered new insights on the genetic causes of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease. These findings could uncover a … Continue Reading Human generational study pinpoints epigenetic cause of Amyotrophic Lateral Sclerosis (ALS).
One of the major challenges of cocaine addiction is the high rate of relapse after periods of withdrawal and abstinence. Now, new research from McGill University and Bar Ilan University reveals … Continue Reading Study shows most epigenetic changes happen in cocaine addiction during the periods of withdrawal.
Researchers at Columbia University and Leiden University have found that children whose mothers were malnourished at famine levels during the first 10 weeks of pregnancy had changes in DNA methylation … Continue Reading Epigenomic study pinpoints critical period for prenatal nutrition in development of fetus.
A study from researchers at Massachusetts General Hospital (MGH) and Brigham and Women’s Hospital (BWH) reveals for the first time exactly how mutations associated with the most common form of … Continue Reading Study identifies the epigenetic pathway of familial Alzheimer’s disease.