Category Archives: geroscience

New role for mitochondria identified in cellular senescence and aging.


Age is the largest risk factor for numerous pathologies, ranging from neurodegeneration to cancer. These pathologies likely arise from a loss of tissue homeostasis driven by one or more basic aging process, together with stochastic, genetic, and environmental factors.  Mitochondria have long been hypothesized to be potential drivers of aging phenotypes, with dysfunctional mitochondria shown to accumulate with age in

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