Primary progressive aphasia (PPA) is a form of dementia characterized by degeneration of the language network.  In the early stages, PPA is associated with a left-lateralized pattern of cortical atrophy most commonly leading to frontotemporal degeneration, followed by Alzheimer’s disease.  PPA patients with Alzheimer’s disease generally show a different pattern of neurofibrillary tangles than beta-amyloid plaques, with varying distribution in the brain. However, previous amyloid imaging … Continue reading Neuroimaging can identify start and location of amyloid plaques in living brain.