It is known that during disease, tau protein gets modified, changes its location in nerve cells and then aggregates.  In healthy nerve cells, tau resides in a part of the nerve cell termed the axon, the long, slender part of the cell that carries electrical impulses away from the neuron’s body.  Dendritic mislocalization of microtubule-associated tau protein is a hallmark of tauopathies, however, the role … Continue reading Previously unknown tau pathway leading to Alzheimer’s disease identified.