Mammalian skeletal muscles can regenerate following injury and this response is mediated by a specific type of stem cell, the satellite cell. Significant evidence suggests that while stem cells represent … Continue Reading Previously unknown mechanism in skeletal muscle regeneration identified.
The muscular dystrophies are a group of muscle wasting disorders characterized by progressive weakening and degeneration of striated muscle. The most common form is Duchenne muscular dystrophy (DMD), an X-linked … Continue Reading New treatment strategy for muscular dystrophy sound in preclinical phase.
Limb Girdle Muscular Dystrophy is caused by mutations in any of at least 15 different genes and affects 1 in 14,500 to 1 in 123,000 annually. Individuals with Limb Girdle … Continue Reading Precision medicine for severe muscular dystrophy heads for clinical trials.
When muscle cell membranes are damaged, the repair protein dysferlin is activated and reseals muscle membrane tears. If this repair protein is altered due to a genetic mutation, the body’s … Continue Reading Missing protein restored in patients with Muscular Dystrophy.