New single-cell sequencing technique can track subtle neurogenetic mutations spatially.

DNA sequences were once thought to be identical from cell to cell, but it’s increasingly understood that mutations can arise during brain development that affect only certain groups of brain cells. A technique developed at Boston Children’s Hospital allows these subtle mutation patterns to be traced and mapped spatially for the first time. This capability is a significant advance for genetics research and provides a … Continue reading New single-cell sequencing technique can track subtle neurogenetic mutations spatially.